Condition

Chronic Myelomonocytic Leukemia (CMML) clinical trials and research

• 6Clinical trials
• 2Countries

Newest Chronic Myelomonocytic Leukemia (CMML) clinical trials

All recruiting trials (6)

• Thiotepa-based conditioning regimen before allogeneic stem cell transplant for CMML

  This study tests a thiotepa-containing conditioning plan before an allogeneic stem cell transplant in adults with intermediate-2 or high-risk CMML to see if it improves outcomes.

  Recruiting Peking University People's Hospital · Beijing · NCT07588594

• Early Tacrolimus Taper After Allogeneic Transplant

  This study tests whether stopping tacrolimus early after an allogeneic stem cell transplant is safe and feasible for people with AML, MDS, MF, CML, CMML, or GVHD risk after transplant.

  Recruiting Phase 1 Stanford University · Palo Alto, California · NCT07302776

• Axatilimab plus ruxolitinib for people with myelofibrosis or CMML

  This trial tests whether adding axatilimab, an antibody that targets CSF1R, to ruxolitinib can help control disease and symptoms in adults with myelofibrosis or chronic myelomonocytic leukemia (CMML).

  Recruiting Phase 1/2 M.D. Anderson Cancer Center · Houston, Texas · NCT07128381

• CBX-250 for relapsed or refractory myeloid leukemias.

  This will try CBX-250, a new injectable medicine, in people aged 12 and older with relapsed or refractory AML, high-risk MDS, CMML, or CML to see if it can control disease with tolerable side effects.

  Recruiting at 11 sites Phase 1 Crossbow Therapeutics, Inc. · Duarte, California and 10 other locations · NCT06994676

• Testing STX-0712 in patients with advanced blood cancers

  This study is testing a new drug called STX-0712 to see if it can help people with advanced blood cancers like chronic myelomonocytic leukemia and acute myeloid leukemia who have run out of other treatment options.

  Recruiting at 6 sites Phase 1 Solu Therapeutics, Inc · Stanford, California and 6 other locations · NCT06950034

• Post-transplant cyclophosphamide strategies to prevent graft-versus-host disease after mismatched unrelated donor stem cell transplant

  This platform tests whether adding different drug combinations with post-transplant cyclophosphamide prevents graft‑versus‑host disease better than the standard regimen for adults getting mismatched unrelated donor peripheral blood stem cell transplants for blood cancers.

  Recruiting at 13 sites Phase 2 Center for International Blood and Marrow Transplant Research · Birmingham, Alabama and 12 other locations · NCT06859424

Related topics

Quick answers

How many Chronic Myelomonocytic Leukemia (CMML) clinical trials are recruiting right now?

6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (5 trials), China (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 3, Phase 1/2: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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