Condition
Brain Metastases From Non-small Cell Lung Cancer (NSCLC) clinical trials and research
As of November 12, 2026, Find a Trial lists 5 Brain Metastases From Non-small Cell Lung Cancer (NSCLC) clinical trials that are recruiting, at sites in 3 countries (most in United States (3), Netherlands (1), Vietnam (1)). 1 was first registered in the last 30 days. By phase: Phase 2 (4). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 1New in 30 days
- 3Countries
Newest Brain Metastases From Non-small Cell Lung Cancer (NSCLC) clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Osimertinib Plus SRS/SRT for EGFR-Mutant NSCLC with Symptomatic Brain Metastases | Phase 2 | Ho Chi Minh City | Recruiting | Nov 2, 2026 |
| Ga68-PSMA PET/CT to tell radiation damage from tumor growth in brain metastases | — | Amsterdam | Recruiting | Apr 6, 2026 |
| Same-day stereotactic radiation with reduced planning margins for growing or changing brain metastases | Phase 2 | Boston, Massachusetts | Recruiting | Aug 20, 2025 |
| Preventing first seizures with levetiracetam in patients with motor cortex brain metastases | Phase 2 | Boston, Massachusetts | Recruiting | Aug 19, 2025 |
| Avoiding brain radiation when systemic therapy already targets brain metastases | Phase 2 | Burlington, Vermont | Recruiting | May 15, 2025 |
All recruiting trials (5)
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Osimertinib Plus SRS/SRT for EGFR-Mutant NSCLC with Symptomatic Brain Metastases
This study tests whether adding targeted brain radiotherapy to osimertinib helps control brain metastases in adults with EGFR-mutant NSCLC and neurological symptoms.
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Ga68-PSMA PET/CT to tell radiation damage from tumor growth in brain metastases
This project will test whether a Ga68-PSMA PET/CT scan can tell radiation necrosis apart from tumor regrowth in adults with brain metastases from lung cancer, melanoma, or breast cancer.
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Same-day stereotactic radiation with reduced planning margins for growing or changing brain metastases
This trial will try to see if doing MRI planning and stereotactic radiation on the same day, with either a 0 mm or 1 mm treatment margin, helps adults with growing or unstable brain metastases stay on target and reduce side effects.
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Preventing first seizures with levetiracetam in patients with motor cortex brain metastases
This test will try giving levetiracetam to adults with motor cortex brain metastases who have never had a seizure to see if it prevents a first seizure compared with not giving the drug.
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Avoiding brain radiation when systemic therapy already targets brain metastases
This pilot trial tests whether patients with brain metastases who respond to systemic therapy can skip brain radiation.
Related topics
Quick answers
How many Brain Metastases From Non-small Cell Lung Cancer (NSCLC) clinical trials are recruiting right now?
5, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in United States (3 trials), Netherlands (1 trial), Vietnam (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 4. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.