Condition

Benign Prostatic Hyperplasia (BPH) clinical trials and research

• 8Clinical trials
• 6Countries

Newest Benign Prostatic Hyperplasia (BPH) clinical trials

All recruiting trials (8)

• Compare three tools for removing large prostates: ThuFLEP, HoLEP, and B-TUEP

  This trial tests whether three endoscopic techniques for large prostate removal are safe and effective in men with severe urinary symptoms who have not improved with medicines.

  Recruiting Tanta University · Tanta, Gharbia Governorate · NCT07627178

• GRAIL Pulsed Field Ablation for Enlarged Prostate (BPH) safety and effectiveness

  This study tests whether the ALPFA GRAIL Pulsed Field Ablation system can safely reduce BPH symptoms in men over 45 compared with a sham procedure.

  Recruiting ALPFA Medical · Germantown, Tennessee · NCT07592299

• Transperineal laser ablation to treat persistent obstruction from BPH after minimally invasive procedures

  This test will try in-office transperineal laser ablation (TPLA) to relieve urinary blockage and symptoms in men whose BPH returned after prior minimally invasive treatments.

  Recruiting The Cleveland Clinic · Cleveland, Ohio · NCT07016620

• MRI/TRUS fusion–guided thermal vapor ablation for benign prostatic enlargement

  This will try a targeted steam (thermal vapor) treatment guided by MRI and ultrasound to reduce urinary symptoms in men 45–85 with moderate to severe BPH who have not responded to or declined medications.

  Recruiting Chinese PLA General Hospital · Beijing, Beijing Municipality · NCT06817733

• Comparing Optilume catheter and Rezum water-vapor therapy for enlarged prostate (BPH)

  This compares Optilume catheter and Rezum water-vapor therapy to see which better eases lower urinary tract symptoms in men with enlarged prostates (BPH) sized 30–100 g.

  Recruiting Centre hospitalier de l'Université de Montréal (CHUM) · Montreal, Quebec · NCT06769997

• Investigating the effects of an anti-inflammatory drug on benign prostatic hyperplasia

  This study is testing whether an anti-inflammatory drug can help men with benign prostatic hyperplasia feel better and reduce the size of their prostate.

  Recruiting Phase 2 Endeavor Health · Glenview, Illinois · NCT06062875

• Comparing the safety of iTind and UroLift for treating BPH

  This study is testing whether the iTind device is safer than the UroLift procedure for men over 50 with symptoms from an enlarged prostate.

  Recruiting at 15 sites Olympus Corporation of the Americas · Phoenix, Arizona and 18 other locations · NCT04757116

• Comparing Aquablation and Holmium Laser for Enlarged Prostate Treatment

  This study is testing if a new water-based treatment for enlarged prostates works as well as a traditional laser surgery for men who have symptoms from benign prostatic hyperplasia.

  Recruiting Cantonal Hospital of St. Gallen · Sankt Gallen · NCT04560907

Related topics

Quick answers

How many Benign Prostatic Hyperplasia (BPH) clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (4 trials), Canada (1 trial), Switzerland (1 trial), United Kingdom (1 trial), Egypt (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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