Condition

AML, Adult clinical trials and research

• 18Clinical trials
• 7Countries

Newest AML, Adult clinical trials

All recruiting trials (18)

• Quality-of-life–guided red blood cell transfusions for people with refractory MDS or AML

  We test whether using routine EQ-5D-5L quality-of-life scores to decide when to give red blood cell transfusions can safely reduce the number of transfusions for adults with refractory MDS or AML who are receiving only palliative care.

  Recruiting Centre Hospitalier Universitaire de Nice · Nice · NCT07328191

• Venetoclax plus Azacitidine versus Daunorubicin/Idarubicin plus Cytarabine induction for fit older adults with AML

  This trial will test whether Venetoclax plus Azacitidine works as well as standard daunorubicin or idarubicin plus cytarabine induction in fit adults aged 55–75 with acute myeloid leukemia.

  Recruiting Phase 3 Institute of Hematology & Blood Diseases Hospital, China · Tianjin · NCT07132684

• Post-remission treatments for MRD-positive adult AML

  This study will try different drug regimens to see if they help people aged 14 and older with AML who are in remission but still MRD-positive stay relapse-free and live longer.

  Recruiting Institute of Hematology & Blood Diseases Hospital, China · Tianjin, Tianjin Municipality · NCT07131059

• Venetoclax plus a short (3-day) decitabine schedule for untreated elderly or unfit adults with AML

  This trial will see if venetoclax combined with a short (3-day) decitabine course helps people with newly diagnosed AML who are elderly or cannot receive standard chemotherapy.

  Recruiting The Second Hospital of Hebei Medical University · Hebei · NCT07117422

• Observational study of older patients with acute myeloid leukemia receiving intensive treatment

  This study looks at older patients with acute myeloid leukemia to see how well intensive treatment works for them and what factors might affect their recovery and survival.

  Recruiting at 27 sites French Innovative Leukemia Organisation · Angers and 26 other locations · NCT06891144

• Using eganelisib alone and with cytarabine for treating relapsed/refractory AML

  This study is testing if a new drug called eganelisib, used alone or with another drug called cytarabine, can help people with relapsed or hard-to-treat acute myeloid leukemia feel better.

  Recruiting at 12 sites Phase 1 Stelexis BioSciences · Duarte, California and 11 other locations · NCT06533761

• Real-world outcomes for adults with AML treated with new drugs (BoxTrial)

  This project will follow adults with AML treated in routine care across Italy to see how new approved drugs and combinations perform over at least two years.

  Recruiting at 2 sites Gruppo Italiano Malattie EMatologiche dell'Adulto · San Giovanni Rotondo and 1 other locations · NCT06513273

• CAR-T cell therapy targeting CD33 and CD123 for treating acute myeloid leukemia

  This study is testing a new CAR-T cell therapy that targets specific markers in the blood to see if it can help people with acute myeloid leukemia who haven't responded to other treatments.

  Recruiting Phase 1/2 Essen Biotech · Beijing, Beijing Municipality · NCT06420063

• Observational study on the use of Ivosidenib for patients with Acute Myeloid Leukemia in France

  This study looks at how well a drug called Ivosidenib works for people in France with acute myeloid leukemia who have a specific gene mutation, to see if it helps them feel better or respond to treatment.

  Recruiting at 6 sites French Innovative Leukemia Organisation · Amiens and 20 other locations · NCT06377579

• Combining revumenib with standard chemotherapy and targeted therapy for acute myeloid leukemia

  This study is testing a new treatment combining revumenib with standard chemotherapy and another targeted therapy to see if it helps newly diagnosed patients with a specific type of acute myeloid leukemia.

  Recruiting at 2 sites Phase 1 Dana-Farber Cancer Institute · New Haven, Connecticut and 1 other locations · NCT06313437

• Combining Chidamide and Azacitidine for AML Treatment After Transplant

  This study is testing if combining two drugs, Chidamide and azacitidine, can help people with acute myeloid leukemia who still have some cancer after a stem cell transplant to stay cancer-free longer.

  Recruiting Guangdong Provincial People's Hospital · Guangzhou, Guangdong · NCT06066905

• Combining oral azacitidine with gilteritinib for treating relapsed FLT3-mutated acute myeloid leukemia

  This study is testing if adding an oral medication called azacitidine to gilteritinib can help adults with relapsed FLT3-mutated acute myeloid leukemia feel better and live longer.

  Recruiting at 3 sites Phase 2 French Innovative Leukemia Organisation · Amiens and 19 other locations · NCT06022003

• Assessing a new treatment for older patients with acute myeloid leukemia

  This study is testing a new combination of medications for older adults newly diagnosed with acute myeloid leukemia to see if it can improve treatment while lowering costs.

  Recruiting at 19 sites Phase 2 Stichting Hemato-Oncologie voor Volwassenen Nederland · 's-Hertogenbosch and 18 other locations · NCT06014489

• Evaluating STI-8591 for advanced Acute Myeloid Leukemia

  This study is testing a new drug called STI-8591 to see if it is safe and effective for adults with advanced Acute Myeloid Leukemia.

  Recruiting Phase 1 Zhejiang ACEA Pharmaceutical Co. Ltd. · Hangzhou, Zhejiang · NCT05947344

• Evaluating the impact of geriatric assessments on treatment for older AML patients

  This study is testing if a thorough health check for older adults with newly diagnosed acute myeloid leukemia can help doctors choose better treatments and improve their chances of recovery.

  Recruiting Abramson Cancer Center at Penn Medicine · Philadelphia, Pennsylvania · NCT05909501

• Characterizing genetic and protein changes in adult AML patients with specific rearrangements

  This study is trying to learn more about the genetic and protein changes in adults with a specific type of acute myeloid leukemia to improve understanding and treatment options.

  Recruiting Gruppo Italiano Malattie EMatologiche dell'Adulto · Piacenza · NCT05839392

• Combination treatment for untreated acute myeloid leukemia

  This study is testing a new combination of three medications to see if they can help people with untreated acute myeloid leukemia go into remission.

  Recruiting Phase 2 Shanghai Tong Ren Hospital · Changzhou and 18 other locations · NCT05736965

• Comparing precision therapy to standard therapy for elderly patients with AML and MDS

  This study is testing if a personalized cancer treatment based on genetic information works better and is safer for older patients with acute myeloid leukemia and myelodysplastic syndrome than the usual standard treatment.

  Recruiting Phase 2 University Hospital, Akershus · Lørenskog · NCT05025098

Related topics

Quick answers

How many AML, Adult clinical trials are recruiting right now?

18, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in China (7 trials), France (4 trials), United States (3 trials), Italy (2 trials), Netherlands (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 1: 3, Phase 1/2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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