Condition

Advanced Solid Tumor Cancer clinical trials and research

• 11Clinical trials
• 11Countries

Newest Advanced Solid Tumor Cancer clinical trials

All recruiting trials (11)

• Added tissue or liquid biopsy profiling to guide advanced solid tumor treatment

  This study tests how comprehensive genomic profiling from tumor tissue or blood can help tailor treatment decisions for adults with advanced solid tumors or primary CNS cancers at multiple centers.

  Recruiting at 14 sites The Belgian Society of Medical Oncology · Anderlecht and 13 other locations · NCT07713550

• EASE: A new approach to help adults with advanced cancer cope with fear of progression

  This study tests a written exposure-based coping program to see if it reduces fear of cancer progression and related distress in adults with advanced solid tumors.

  Recruiting at 2 sites University of Colorado, Boulder · Aurora, Colorado and 1 other locations · NCT07636200

• First-in-human test of ZE94-0605 for advanced solid tumors

  This first-in-human trial tests ZE94-0605, an oral CDK2 inhibitor, in adults with advanced or metastatic solid tumors to find a safe dose and explore early signs of activity.

  Recruiting at 3 sites Phase 1 Eilean Therapeutics · Kogarah, New South Wales and 2 other locations · NCT07524140

• HC010 with chemotherapy for advanced gastrointestinal cancers

  This Phase Ib test will see if adding HC010 to common chemotherapy is safe and shows early benefit for people with advanced gastrointestinal cancers.

  Recruiting Phase 1 HC Biopharma Inc. · Beijing · NCT07477743

• BNT3214 for adults with advanced solid tumors

  This trial will test whether the experimental drug BNT3214 is safe and shows signs of benefit for adults whose advanced solid tumors have progressed after standard treatments.

  Recruiting at 6 sites Phase 1/2 BioNTech SE · Clayton and 15 other locations · NCT07455734

• Phase II LM-24C5 treatment for CEACAM5-positive advanced solid tumors

  This trial tests whether giving LM-24C5 together with other therapies is safe and helps adults (18–80) who have CEACAM5-positive advanced solid tumors.

  Recruiting Phase 2 LaNova Medicines Limited · Fuzhou, Fujian and 1 other locations · NCT07387081

• HC010 combined with chemotherapy for advanced lung cancer — Phase Ib dosing and safety

  This trial tests whether adding HC010 to standard chemotherapy is safe and finds the best dose in people with advanced lung cancer while looking for early signs it helps.

  Recruiting Phase 1 HC Biopharma Inc. · Guangzhou, Guangdong · NCT07381829

• Trastuzumab rezetecan for HER2-positive advanced solid tumors resistant to standard treatments

  This treatment gives trastuzumab rezetecan every three weeks to see if it helps adults with HER2-positive advanced solid tumors — including extramammary Paget's disease, rare tumors like urachal cancer, and urothelial carcinoma — that have stopped responding to standard treatments.

  Recruiting Phase 2 Fudan University · Shanghai, Shanghai Municipality · NCT07309770

• YK1101 TCR‑T cell therapy targeting MAGE‑A4 for advanced solid tumors

  This will test whether YK1101, a personalized T cell therapy that targets MAGE‑A4, is safe and can help adults with advanced MAGE‑A4–positive solid tumors who are HLA‑A*11:01 positive.

  Recruiting Phase 1 Peking University · Beijing and 1 other locations · NCT07139067

• Testing ABBV-CLS-484 for advanced solid tumors

  This study is testing a new treatment called ABBV-CLS-484 for people with advanced solid tumors that haven't improved with standard therapies to see how well it works on its own and with other treatments.

  Recruiting at 28 sites Phase 1 Calico Life Sciences LLC · Tucson, Arizona and 29 other locations · NCT04777994

• X-ray activated cancer therapy for advanced tumors

  This study is testing a new injection therapy that uses X-rays to see if it can safely help people with advanced head and neck cancer, breast cancer, soft tissue sarcoma, or melanoma.

  Recruiting at 4 sites Phase 1 Immunolight, LLC · Washington D.C., District of Columbia and 3 other locations · NCT04389281

Related topics

Quick answers

How many Advanced Solid Tumor Cancer clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in China (6 trials), United States (3 trials), Australia (2 trials), South Korea (2 trials), Taiwan (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 6, Phase 2: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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