Yoga program to improve function in people with knee osteoarthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized, concealed-allocation interventional comparison of a structured yoga program versus a conventional therapeutic exercise program for people with knee osteoarthritis. About 90 participants (approximately 45 per group) aged 45 years or older with a clinical diagnosis of knee osteoarthritis will be enrolled and undergo baseline assessments before randomization. Participants will be allocated 1:1 to either the yoga intervention or the therapeutic exercise control and will complete the assigned exercise program with follow-up functional assessments. The primary focus is on change in functionality, with eligibility limited to Kellgren–Lawrence grade 1–3 and exclusion of conditions that would preclude safe exercise.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* A clinical diagnosis of knee osteoarthritis (knee pain for \> 3 months)
* Morning stiffness \<30 minutes
* Crepitus
* Bone tenderness, and absence of palpable heat and/or diagnosis established radiographically (determined by Kellgren and Lawrence grade 1 to 3 on a scale 1 up to 4)

Exclusion Criteria:

* Bilateral hip or KOA
* Severe osteoporosis
* Fibromyalgia
* Clinical history of tumors or cancer
* Active inflammatory joint diseases (rheumatoid arthritis, gout), undergoing any joint replacement of the lower extremity
* Neurological diseases (Parkinson's disease, Stroke, Multiple Sclerosis, muscular dystrophies, neuromotor disease, Alzheimer's disease)
* Infected wounds or osteomyelitis in the knee region
* Deep vein thrombosis or thrombophlebitis, sensory changes in the lower limbs
* A cognitive and cardiopulmonary impairment that may prevent or limit the performance of exercises
* Use of a walking assistance device, history of recent trauma to the knee
* Be performing or having prior any form of treatment involving physiotherapy, intra-articular corticosteroids, anti-inflammatories, opioid medication, or chondroprotective in the six months before the start of interventions

Where it's running

• University of Nove de Julho
  São Paulo, Brazil Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.