Yoga-based group program plus usual care for outpatients with schizophrenia spectrum disorders

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

A three-arm, rater-blinded randomized pilot in Berlin compares a yoga-based group intervention plus treatment as usual (YoGI + TAU) to strength and flexibility training plus TAU (SFT + TAU) and to TAU alone. Participants are psychiatric outpatients aged 18–65 with a schizophrenia spectrum diagnosis and low-to-moderate psychotic symptoms, randomized in blocks and informed of group allocation after randomization. Self-report and blinded clinician ratings are collected at baseline, after 12 weeks, and at a 3-month follow-up, and acute stress and perceived effort are measured before and after each session. Recruitment, consent, and assessments are managed by blinded psychologists at Charité and participants receive €50 upon completion.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of Schizophrenia Spectrum Disorder by previous (medical) reports according to ICD-10/ DSM-V
* Treated as psychiatric outpatients
* Age between 18 and 65 years
* Ability to give informed consent
* Willingness and ability to engage in psychotherapeutic group therapy
* Low to moderate psychotic state indicated with a score of ≤ 6 for each item at the Positive scale of the Positive and Negative Syndrome Scale (PANSS, Peralta \& Cuesta, 1994)

Exclusion Criteria:

* Neurological disorders and history of severe traumatic brain injury in the past that may affect cognitive functioning
* Acute substance dependence, excluding nicotine and prescribed medication
* PANSS-P score on one item \> 6 (= very severe)
* Ineligibility for group participation
* Acute suicidality, indicated by a score \> 1 on item 8 of the Calgary Depression Scale for Schizophrenia (Addington, Addington, Maticka-Tyndale, \& Joyce, 1992)
* Conflicting co-therapy such as electroconvulsive therapy or ketamine treatment as well as intensive psychotherapy

Where it's running

• Charité - Universitätsmedizin Berlin Klinik für Psychiatrie und Psychotherapie, Campus Charité Mitte
  Berlin, Germany Recruiting

Study contacts

• Study coordinator: Kerem Böge, Prof. Dr. Dr.
• Email: kerem.boege@charite.de
• Phone: +4930450517319

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.