Wrist Injury Strengthening Exercise added to usual care for improving pain and function after a wrist fracture
Official title: Progressive Resistance and Flexibility Exercises Versus Usual Care Advice for Improving Pain and Function After Distal Radius Fracture in Adults Aged 50 Years or Over in Denmark: the WISE-DK Randomised Trial
Run by University of Aarhus · NCT07538323 · Data updated 2026-11-12
This trial tests whether a therapist-guided strengthening program helps people 50 and older recover better from a wrist fracture than standard self-management advice.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 50 Years and up |
| Sex | All |
| Enrollment | 588 (estimated) |
| Sponsor | University of Aarhus Academic / other |
| Locations | 1 site (Aarhus N) |
| Status | Recruiting |
| Started | May 12, 2026 |
| Main results expected | December 2029 |
| Study ends | December 2029 |
| Registry record updated | November 3, 2026 |
| Trial ID | NCT07538323 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 50 and older with a distal radius fracture (surgically or non-surgically treated) willing to consent and able to participate in therapy and electronic questionnaires.
✕Probably not a fit
Patients with fractures older than two months, open fractures greater than Gustilo type I, cognitive impairment, or inability to participate in the therapy or complete electronic questionnaires may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized approach compares a supervised strengthening exercise program to usual care advice for adults aged 50 and older with a wrist fracture. Participants in the intervention arm receive a therapy session up to 60 minutes plus two follow-up sessions up to 30 minutes each, in addition to usual care. The study uses the Patient Rated Wrist Evaluation to measure pain and function at six months post-injury. Outcomes will be compared to those receiving only usual care, which consists of self-management guidance. The trial is conducted at Aarhus University Hospital in Denmark with lead sponsorship from the University of Aarhus.
Why it matters
Potential benefit: If successful, participants may experience greater improvement in pain and wrist function after a fracture.
How similar studies have gone: Prior studies with supervised rehabilitation approaches have shown promise in improving recovery after wrist injuries, though this exact program and population are specified for this trial.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Distal radius fracture treated surgically or non-surgically * Willing and able to give informed consent Exclusion Criteria: * Injury is more than two months old * There is evidence that the patient would be unable to participate in therapy or a self-guided exercise program provided by a participating center or adhere to study procedures (including cognitive impairment and fracture/surgery complications such as Complex Regional Pain Syndrome) * No e-mail address to receive electronic questionnaires * Open fractures with a Gustilo \& Anderson grading \>1
Where it's running
-
Aarhus University Hospital
Aarhus N, Denmark Recruiting
Study contacts
- Principal investigator: Inger Mechlenburg, DMSc — Aarhus University Hospital
- Study coordinator: Inger Mechlenburg, DMSc
- Email: inger.mechlenburg@clin.au.dk
- Phone: +45 21679062
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.