Work and education outcomes for adults diagnosed with IBD in childhood
Occupational Insertion and Educational Level of Adult Patients With Pediatric Early Inflammatory Bowel Disease (IBD)
This project will see if adults who were diagnosed with Crohn's disease or ulcerative colitis as children have different job and education outcomes compared with the general population.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 460 (estimated) |
| Ages | 25 Years and up |
| Sex | All |
| Sponsor | University Hospital, Lille Academic / other |
| Locations | 1 site (Lille) |
| Trial ID | NCT04887428 on ClinicalTrials.gov |
What this trial studies
This observational project uses the EPIMAD registry to compare occupational insertion and educational level of adults diagnosed with pediatric-onset IBD to those of the general population. Eligible participants are adults aged 25 or older who were diagnosed before age 17 between 1988 and 2011 and reside in the EPIMAD catchment area. The study analyzes differences by disease type, sex, age at diagnosis (< or ≥10 years), surgery history, disease location, treatments, and quality of life, and collects patient-reported perceptions of the disease's impact. It also intends to estimate QALYs and assess the responsiveness of the IBD-DI functional handicap score in a subset of approximately 200 patients.
Who should consider this trial
Good fit: Adults aged 25 or older who were diagnosed with Crohn's disease, ulcerative colitis, or related pediatric-onset colitis before age 17, are listed in the EPIMAD registry, and reside in Nord, Pas-de-Calais, Somme, or Seine-Maritime.
Not a fit: People diagnosed after age 17, those not listed in the EPIMAD registry, or individuals living outside the specified French regions are unlikely to be included or directly benefit from the study's local comparisons.
Why it matters
Potential benefit: If successful, the findings could identify gaps in education and employment support and inform services to improve long-term social and occupational outcomes for people with pediatric-onset IBD.
How similar studies have performed: Prior observational studies have shown links between IBD and reduced work participation and quality of life in adults, but data specifically focused on pediatric-onset cohorts are limited, so this approach builds on existing evidence while addressing a gap.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male or female, aged 25 and over at the time of the study * Subject listed in the EPIMAD registry suffering from certain or probable Crohn's disease, or certain or probable ulcerative colitis, or certain or probable ulcerated proctitis, unclassified colitis, diagnosed between 01/01 / 1988 and 12/31/2011, with an age at diagnosis of less than 17 years (definition of the pediatric cohort of the EPIMAD Registry) * Patient residing in the area of the EPIMAD registry: Nord, Pas-de-Calais, Somme or Seine-Maritime * Patient not opposed to the research * Patient not having objected to the use of their data for ancillary studies when registering in the EPIMAD register Exclusion Criteria: * None
Where this trial is running
Lille
- Hop Jeanne de Flandre Chu Lille — Lille, France (Recruiting)
Study contacts
- Principal investigator: Dominique Turck, MD,PhD — University Hospital, Lille
- Study coordinator: Dominique Turck, MD,PhD
- Email: Dominique.Turck@CHRU-Lille.fr
- Phone: 320446885
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.