Weight loss program for patients who had pre-eclampsia
Weight Loss Following an Episode of Pre-eclampsia Using a Dissociated or Hypocaloric Diet in Overweight or Obese Patients
This study is testing two different diet plans to help overweight women who had pre-eclampsia lose weight while keeping their muscle, to see which one works better for their health.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | Female |
| Sponsor | Centre Hospitalier le Mans Academic / other |
| Locations | 1 site (Le Mans) |
| Trial ID | NCT06067906 on ClinicalTrials.gov |
What this trial studies
This project aims to help overweight and obese patients who have experienced pre-eclampsia to reduce their body mass index (BMI) without losing lean body mass. Participants will choose between two dietary approaches: a hypocaloric diet or a dissociated diet, both of which have been minimally studied in the context of post-pre-eclampsia management. The study focuses on nutritional management tailored to individual preferences, with the goal of addressing the link between pre-eclampsia, obesity, and chronic kidney disease.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 18 to 45 who have had pre-eclampsia in the last five years and have a BMI between 25 kg/m² and 40 kg/m².
Not a fit: Patients with cognitive disorders, eating disorders, or those unable to provide informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could provide a tailored weight loss solution that improves health outcomes for patients who have experienced pre-eclampsia.
How similar studies have performed: While the specific dietary approaches have seen limited investigation, similar studies targeting weight management in post-pre-eclampsia patients have shown promise.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Person affiliated to social security * Free, informed and written consent signed by the participant and the investigator (no later than the day of day of inclusion and before any examination required by the research) * Patient over 18 years of age at the time of inclusion and \< 45 years of age * Having had an pre-eclampsia in the last 5 years according to the definitions of the ISSHP 2018 * Patient with a BMI between 25 kg/m² and 40 kg/m² who accepts dietetic follow up * Patient with a medical prescription for dietetic follow-up aimed at losing weight loss * Patient with a balanced diet Exclusion Criteria: * Patients with a mental disability or language barrier that prevents them from understanding or consenting to the study * Patients deprived of their liberty by judicial or administrative decision * Patients under psychiatric care * Patients subject to a legal protection measure * Patients with cognitive disorders or defined eating disorders * Patients who are pregnant or breast-feeding * Patients undergoing steroid treatment and/or immunosuppression * Have been on a low-calorie or dissociated diet for at least 6 months * Patients with CKD stage ≥ 3A
Where this trial is running
Le Mans
- Centre Hospitalier Du Mans — Le Mans, France (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.