Weight loss intervention using ketogenic meals
Weight Loss Interventions for Obesity
NA · National University Hospital, Singapore · NCT06022796
This study is testing if healthy ready-to-eat ketogenic meals paired with a nutrition app can help people with obesity in Singapore lose weight better than just using the app with a regular ketogenic diet.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 21 Years to 75 Years |
| Sex | All |
| Sponsor | National University Hospital, Singapore (other) |
| Locations | 1 site (Singapore) |
| Trial ID | NCT06022796 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of healthy ketogenic ready-to-eat meals combined with a mobile health nutrition application compared to a healthy ketogenic diet without meal provision, both utilizing the app. The aim is to facilitate weight loss and improve metabolic outcomes among individuals with obesity in Singapore. The research addresses barriers to weight management, such as motivation and appetite control, by providing convenient meal options and self-monitoring tools. Participants will be randomly assigned to one of the two intervention groups to assess the impact on weight loss.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 21 to 75 with a BMI of 27.5 or higher who own a smartphone and are literate in English.
Not a fit: Patients who are pregnant, lactating, have certain medical conditions like diabetes on insulin treatment, or severe psychiatric disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly aid individuals with obesity in achieving weight loss and improving their metabolic health.
How similar studies have performed: While the ketogenic diet has shown benefits for weight management, this specific approach using ready-to-eat meals and mHealth applications is relatively novel and has not been extensively tested in previous studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 21 to 75 years old * Body Mass Index \>= 27.5kg/m2 * Own a smartphone * Literacy in English * NUH staff Exclusion Criteria: * Intention of pregnancy; Pregnancy; Lactating individuals * Type 1 Diabetes Mellitus or Type 2 Diabetes Mellitus on insulin treatment * Untreated Endocrinopathy (e.g., hyper/hypothyroidism) * Advanced kidney disease * Abnormal liver function test assessed at screening * Heart diseases * Severe cognitive or psychiatric disabilities/disorders (e.g., eating disorders, depression) * Active malignancies * Taking medications that affect appetite or induce weight loss; previous or plans for bariatric surgery.
Where this trial is running
Singapore
- National University Hospital — Singapore, Singapore (RECRUITING)
Study contacts
- Study coordinator: Melissa Tay
- Email: melissa_hj_tay@nuhs.edu.sg
- Phone: 67725166
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Overweight, Weight Loss, Ketogenic Dieting, Obesity