Vocal biomarkers for health monitoring in a longitudinal population cohort
Official title: VOCAL BIOMARKERS FOR HEALTH MONITORING: AN OPEN LONGITUDINAL HYBRID COHORT STUDY
Run by Luxembourg Institute of Health · NCT07665229 · Data updated 2026-11-12
Researchers are testing whether voice features can help track health over time in adults, including those with and without health conditions.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 3700 (estimated) |
| Sponsor | Luxembourg Institute of Health Government |
| Locations | 1 site (Luxembourg) |
| Status | Recruiting |
| Started | September 1, 2026 |
| Main results expected | May 2031 |
| Study ends | May 2031 |
| Registry record updated | September 22, 2026 |
| Trial ID | NCT07665229 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 years or older who speak FR/EN/DE/PT, own a compatible smartphone, and can provide informed consent.
✕Probably not a fit
Individuals who do not own a compatible smartphone or who are unable to provide informed consent may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an observational, open longitudinal cohort study led by the Luxembourg Institute of Health. The project will collect voice recordings over time from adults who speak French, English, German, or Portuguese and own a compatible smartphone, to explore how vocal features relate to health status. The study aims to create a diverse dataset across multiple pathologies and no pathology, to position voice as a potential new health indicator. Data will be used to examine how concomitant diseases influence voice signatures and to support future digital health tools and patient monitoring.
Why it matters
Potential benefit: If successful, results could enable remote health monitoring through simple voice-based measures and improve early detection of health changes.
How similar studies have gone: Earlier work in vocal biomarkers shows promise, but broad clinical routine use remains exploratory and requires further validation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults ≥ 18 years. * Able to understand the study, provide informed consent and comply with study procedures (with reasonable accommodations as needed). * Speaks one of the study languages (FR/EN/DE/PT). * Owns a smartphone compatible with the study app. Exclusion Criteria: * \- Acute clinical instability at inclusion (e.g., need for immediate medical care, severe respiratory distress, hospitalized patients not allowed to go out of their room) where study procedures could interfere with care. * Any other condition that, in the judgement of the Medical PI or delegated qualified staff, would place the participant at unreasonable risk or prevent meaningful participation, despite accommodations.
Where it's running
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Clinical and Epidemiological Investigation Center CIEC- LCTR
Luxembourg, Luxembourg Recruiting
Study contacts
- Principal investigator: Guy Fagherazzi, PhD — Luxembourg Institute of Health
- Study coordinator: Aurélie Fischer, PhD
- Email: aurelie.fischer@lih.lu
- Phone: 0035226970230
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.