Vivifrail exercise for frailty in older adults with COPD
Official title: Frailty in Older Adults With Chronic Obstructive Pulmonary Disease (COPD) and Outcomes of the VIVIFRAIL Program
Run by National Geriatric Hospital · NCT07519603 · Data updated 2026-11-12
This study will test whether the Vivifrail exercise program helps older adults (60+) with COPD and frailty improve physical function, daily activities, and quality of life.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 60 Years and up |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | National Geriatric Hospital Government |
| Locations | 2 sites (Hanoi, Hanoi and 1 other locations) |
| Status | Recruiting |
| Started | March 1, 2026 |
| Main results expected | December 1, 2026 |
| Study ends | January 1, 2027 |
| Registry record updated | April 9, 2026 |
| Trial ID | NCT07519603 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 60 or older with COPD by GOLD criteria who are clinically stable, physically able to take part in exercise, and can give informed consent.
✕Probably not a fit
Patients with recent COPD exacerbation, severe cardiovascular disease or musculoskeletal limitations, severe cognitive impairment, or those unable to participate in exercise are unlikely to benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Researchers will screen older adults with COPD at Hospital 198 in Hanoi to determine how common frailty is in this population and to enroll eligible participants into an interventional comparison of the Vivifrail exercise program versus usual care. Participants who meet inclusion criteria (age ≥60, stable COPD, able to exercise) will follow a tailored Vivifrail exercise regimen while the control group receives usual care, with outcomes measured over the study period. Primary outcomes include physical performance, activities of daily living, and quality of life, with additional monitoring for safety and adverse events. The trial is conducted at the National Geriatric Hospital site within Hospital 198, Ministry of Public Security in Hanoi, Vietnam.
Why it matters
Potential benefit: If successful, the program could improve strength, balance, daily functioning, and overall quality of life for older adults with COPD and frailty.
How similar studies have gone: Previous studies in general older populations have shown Vivifrail improves muscle strength and function, but evidence specifically in older adults with COPD and in Vietnam is limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 60 years * Diagnosis of COPD according to GOLD criteria * Clinically stable COPD (no exacerbation within the past 4 weeks) * Able to participate in exercise training * Provide informed consent Exclusion Criteria: * Acute COPD exacerbation within the past 4 weeks * Severe cardiovascular disease limiting exercise * Severe cognitive impairment * Musculoskeletal disorders preventing exercise * Participation in another clinical trial
Where it's running
-
Hospital 198, Ministry of Public Security
Hanoi, Hanoi, Vietnam Recruiting -
Hospital 198, Ministry of Public Security
Hanoi, Vietnam Recruiting
Study contacts
- Principal investigator: Diu Thi Vu, MD, MSc — Hanoi Medical University, Vietnam; Hospital 198, Ministry of Puplic Security, Vietnam; National Geriatric Hospital, Vietnam
- Study coordinator: Diu Thi Vu, MD, MSc
- Email: vudiu198@gmail.com
- Phone: +84 912 088 986
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.