Vitamin D to prevent recurrent pre-eclampsia in pregnant women

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, placebo-controlled Phase 4 trial enrolls pregnant women with a history of pre-eclampsia at the antenatal clinic of Nishtar Medical University and Hospital in Multan. Participants are randomized to receive either 4,000 IU oral vitamin D daily or a matching placebo until 36 weeks' gestation, alongside standard antenatal care. Women attend clinic visits every two weeks for blood pressure checks, and urine protein testing is performed if blood pressure reaches 140/90 mmHg or higher. The trial compares rates of recurrent pre-eclampsia between groups to see if supplementation reduces recurrence.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Gestational age ≥ 20-weeks (on LMP method) ' - Past medical history of pre-eclampsia

Exclusion Criteria:

* Pre-existing hypertension, cardiac diseases, renal disease, thyrotoxicosis (on history and medical record)
* Women presenting with intra-uterine death of the fetus.

Where it's running

• Nishtar Medical University and Hospital
  Multan, Punjab Province, Pakistan Recruiting

Study contacts

• Study coordinator: Tehseen A Principal Investigator, MBBS
• Email: tehseenaslam451@gmail.com
• Phone: +92 303 7832417

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.