Clinical trial Recruiting at 2 sites Observational Ages 18 to 40 Women only

Vitamin D Level at Frozen Embryo Transfer and Pregnancy Outcomes

Official title: Vitamin D Levels and Pregnancy Outcomes Following Frozen Embryo Transfer (FET) in the UAE

Run by Fakih IVF Fertility Center · NCT07681115 · Data updated 2026-11-12

This study looks at whether a woman's vitamin D level on the day of frozen embryo transfer affects her chances of pregnancy and delivering a baby.

More Vitamin D Insufficiency trials

Quick facts

Study typeObservational
Ages18 Years to 40 Years
SexWomen only
Enrollment126 (estimated)
SponsorFakih IVF Fertility Center
Academic / other
Locations2 sites (Abu Dhabi and 1 other locations)
StatusRecruiting
StartedJune 1, 2026
Main results expectedJune 2027
Study endsAugust 2027
Registry record updatedNovember 10, 2026
Trial IDNCT07681115 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Women aged 18–40 undergoing frozen embryo transfer at Fakih IVF who had vitamin D levels measured within the prior three months.

Probably not a fit

Results may show no association between vitamin D levels at FET and pregnancy outcomes, offering no targeted benefit for vitamin D management in this setting.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study in the UAE examines whether serum vitamin D3 levels at the time of frozen embryo transfer are associated with pregnancy and live birth outcomes. Vitamin D status will be categorized as deficient, insufficient, or sufficient, and supplementation history will be collected. The analysis will focus on women undergoing FET at Fakih IVF, with data gathered from medical records and patient questionnaires. The study aims to clarify whether correcting vitamin D insufficiency around FET influences reproductive success. Results could influence vitamin D screening and supplementation practices in fertility clinics.

Why it matters

Potential benefit: If vitamin D status is linked to better outcomes, clinics might optimize screening and supplementation to improve IVF success rates.

How similar studies have gone: Previous prospective studies have shown mixed results; some found no clear benefit of vitamin D supplementation on ongoing pregnancy or live birth in FET, indicating this remains an area needing higher-quality data.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion:

* Women undergoing frozen embryo transfer (FET) at Fakih IVF.
* Age between 18 and 40 years.
* Body mass index (BMI) between 18 and 40 kg/m².
* Patients who had serum vitamin D levels assessed within three months prior to FET
* Supplementation with Vitamin D if deficient \< 30 ng/mL (75 nmol/L).

Exclusion:

* Age below 18 years or above 40 years.
* BMI below 18 kg/m² or above 40 kg/m².
* Patients who did not have vitamin D levels measured within three months prior to FET.
* Patients who were found to have low vitamin D levels but did not receive supplementation.
* Patients with recurrent implantation failure (RIF).
* Patients with known uterine factors affecting implantation (e.g., congenital uterine anomalies, intrauterine adhesions, submucosal fibroids).
* Patients with significant medical comorbidities that may affect pregnancy outcomes.

Where it's running

  • Fakih IVF Fertility Centre LLC
    Abu Dhabi, United Arab Emirates
    Recruiting
  • First IVF Fertility Centre
    Abu Dhabi, United Arab Emirates
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Biofortified eggs to boost vitamin D in healthy adults

    Aiming to see if eating eggs enriched with vitamin D3 or its active form can raise vitamin D levels in healthy adults with low vitamin D.

    Recruiting Cornell University · Ithaca, New York · NCT07859280

  • Vitamin D and its link to bone health, muscle strength, and pain in hospitalized neurological patients

    This trial will test whether giving vitamin D to hospitalized adults with stroke, spinal cord injury, or traumatic brain injury helps bone density, body composition, strength, physical performance, and pain.

    Recruiting at 2 sites Dionyssiotis, Yannis, M.D. · Nea Liosia, Athens and 1 other locations · NCT06791044

  • Evaluating vitamin D's role in sarcoidosis

    This study is testing if giving vitamin D to people with sarcoidosis who have low levels of it can help reduce their symptoms compared to those who get a placebo.

    Recruiting Phase 4 University of Texas Southwestern Medical Center · Dallas, Texas · NCT03621553

  • High-Dose Vitamin D3 in Athletes

    This study tests whether taking 4,000 IU of vitamin D3 daily for 4 or 8 weeks will change hormones, neuromuscular function, cognition, and body composition in athletes who may be vitamin D deficient.

    Recruiting The Jerzy Kukuczka Academy of Physical Education in Katowice · Katowice, Mikołowska 72a · NCT07641075

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.