Vitamin D Level at Frozen Embryo Transfer and Pregnancy Outcomes
Official title: Vitamin D Levels and Pregnancy Outcomes Following Frozen Embryo Transfer (FET) in the UAE
Run by Fakih IVF Fertility Center · NCT07681115 · Data updated 2026-11-12
This study looks at whether a woman's vitamin D level on the day of frozen embryo transfer affects her chances of pregnancy and delivering a baby.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 40 Years |
| Sex | Women only |
| Enrollment | 126 (estimated) |
| Sponsor | Fakih IVF Fertility Center Academic / other |
| Locations | 2 sites (Abu Dhabi and 1 other locations) |
| Status | Recruiting |
| Started | June 1, 2026 |
| Main results expected | June 2027 |
| Study ends | August 2027 |
| Registry record updated | November 10, 2026 |
| Trial ID | NCT07681115 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women aged 18–40 undergoing frozen embryo transfer at Fakih IVF who had vitamin D levels measured within the prior three months.
✕Probably not a fit
Results may show no association between vitamin D levels at FET and pregnancy outcomes, offering no targeted benefit for vitamin D management in this setting.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study in the UAE examines whether serum vitamin D3 levels at the time of frozen embryo transfer are associated with pregnancy and live birth outcomes. Vitamin D status will be categorized as deficient, insufficient, or sufficient, and supplementation history will be collected. The analysis will focus on women undergoing FET at Fakih IVF, with data gathered from medical records and patient questionnaires. The study aims to clarify whether correcting vitamin D insufficiency around FET influences reproductive success. Results could influence vitamin D screening and supplementation practices in fertility clinics.
Why it matters
Potential benefit: If vitamin D status is linked to better outcomes, clinics might optimize screening and supplementation to improve IVF success rates.
How similar studies have gone: Previous prospective studies have shown mixed results; some found no clear benefit of vitamin D supplementation on ongoing pregnancy or live birth in FET, indicating this remains an area needing higher-quality data.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion: * Women undergoing frozen embryo transfer (FET) at Fakih IVF. * Age between 18 and 40 years. * Body mass index (BMI) between 18 and 40 kg/m². * Patients who had serum vitamin D levels assessed within three months prior to FET * Supplementation with Vitamin D if deficient \< 30 ng/mL (75 nmol/L). Exclusion: * Age below 18 years or above 40 years. * BMI below 18 kg/m² or above 40 kg/m². * Patients who did not have vitamin D levels measured within three months prior to FET. * Patients who were found to have low vitamin D levels but did not receive supplementation. * Patients with recurrent implantation failure (RIF). * Patients with known uterine factors affecting implantation (e.g., congenital uterine anomalies, intrauterine adhesions, submucosal fibroids). * Patients with significant medical comorbidities that may affect pregnancy outcomes.
Where it's running
-
Fakih IVF Fertility Centre LLC
Abu Dhabi, United Arab Emirates Recruiting -
First IVF Fertility Centre
Abu Dhabi, United Arab Emirates Recruiting
Study contacts
- Principal investigator: Dr. Michael Fakih, MD — Fakih IVF Abu Dhabi
- Study coordinator: Dr. Lamiya Mohiyiddeen, MD, FRCOG
- Email: lamiya.mohiyiddeen@fakihivf.com
- Phone: +971543676002
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Biofortified eggs to boost vitamin D in healthy adults
Aiming to see if eating eggs enriched with vitamin D3 or its active form can raise vitamin D levels in healthy adults with low vitamin D.
-
Vitamin D and its link to bone health, muscle strength, and pain in hospitalized neurological patients
This trial will test whether giving vitamin D to hospitalized adults with stroke, spinal cord injury, or traumatic brain injury helps bone density, body composition, strength, physical performance, and pain.
-
Evaluating vitamin D's role in sarcoidosis
This study is testing if giving vitamin D to people with sarcoidosis who have low levels of it can help reduce their symptoms compared to those who get a placebo.
-
High-Dose Vitamin D3 in Athletes
This study tests whether taking 4,000 IU of vitamin D3 daily for 4 or 8 weeks will change hormones, neuromuscular function, cognition, and body composition in athletes who may be vitamin D deficient.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.