Clinical trial Recruiting at 1 site Interventional Ages 18 to 99

Visual illusion therapy plus conventional exercises for improving upper limb function after incomplete spinal cord injury

Official title: Effectiveness of Virtual Bodily Illusion Intervention in Upper Limb Motor Function, Sensibility and Pain in People With Incomplete Spinal Cord Injury.

Run by University of Valencia · NCT05142943 · Data updated 2026-11-12

This trial tests whether adding visual illusion therapy to standard exercises helps people with incomplete spinal cord injury improve upper-limb movement.

Quick facts

Study typeInterventional
Ages18 Years to 99 Years
SexAll
Enrollment80 (estimated)
SponsorUniversity of Valencia
Academic / other
Locations1 site (Valencia, Valencia)
StatusRecruiting
StartedNovember 1, 2021
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedJuly 7, 2026
Trial IDNCT05142943 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with incomplete cervical spinal cord injury (AIS C, D, or E) who can understand instructions (MMSE > 23).

Probably not a fit

Patients with non-incomplete SCI, significant comorbidities, or those unable to engage with visual illusion therapy may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants with incomplete cervical spinal cord injury will receive a program combining visual illusion therapy with conventional exercises, with assessments one day before, one day after, and one month later. The study aims to see if this approach enhances motor function, sensation, and muscle tone via neuroplastic changes in the corticospinal pathway and motor cortex. Interventions include visual illusion, physical exercise, and a sham visual illusion control. The trial is conducted at the University of Valencia and uses standard inclusion criteria such as AIS C/D/E and adequate cognitive function, with exclusion criteria excluding traumatic upper limb injuries and other CNS or vestibular disorders.

Why it matters

Potential benefit: If successful, patients may experience improved upper-limb function and quality of life after incomplete spinal cord injury.

How similar studies have gone: Previous research suggests neuroplasticity-targeted therapies can aid recovery, but the effectiveness of visual illusion combined with exercise for this population is still being explored.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Incomplete cervical spinal cord injury (AIS C, D or E).
* Ability to understand instructions (Mini-Mental State Examination\> 23 points)

Exclusion Criteria:

* Traumatic pathology in upper limbs.
* Other alterations of the central nervous system or peripheral
* Alterations in the vestibular system.
* Concomitant diseases.

Where it's running

  • Facultat de Fisioteràpia, Universitat de València
    Valencia, Valencia, Spain
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.