tSCS with rehabilitation for improving movement after spinal cord injury

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial investigates safety and potential benefits of combining transcutaneous spinal cord stimulation (tSCS) with structured rehabilitation in adults with paraplegia from spinal cord injury. Participants receive tSCS targeting the thoracolumbar region alongside ongoing rehabilitation to see if this combo improves voluntary movement beyond tSCS alone. Outcomes will focus on movement restoration and the occurrence of adverse events during the treatment period. The study aims to determine if the protocol can be applied to a larger group of paraplegic patients and is currently conducted at Beijing Tsinghua Chang Gung Hospital.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 18 and 60 years old;
* Spinal cord injury classified as AIS Grade A, B, C, or D, with the distance between the injury level and the conus medullaris at least 60mm
* Able to cooperate with rehabilitation training;
* Stable and healthy physiological condition, as determined by the researcher; must be able to complete the entire study period and cooperate with rehabilitation training.

Exclusion Criteria:

* 1\. Obvious mental disorders (anxiety, depression, etc.) resulting in inability to complete relevant subjective assessments2. Presence of mental or cognitive impairments preventing participation in transcutaneous spinal electrical stimulation and follow-up3. Severe autonomic reflex disorders4. Severe muscle atrophy or joint contractures5. Life expectancy less than 1 year6. Progressive spinal instability or severe spinal deformities7. Uncontrolled hypertension, severe heart disease, or serious medical/respiratory conditions8. Severe hydronephrosis or renal dysfunction9. Individuals considered unsuitable by the researcher

Where it's running

• Beijing Tsinghua Chang Gung Hospital
  Beijing, China Recruiting

Study contacts

• Principal investigator: Yang Lu — Beijing Tsinghua Chang Gung Hospital
• Study coordinator: Yang Lu, MD
• Email: yanglu@btch.edu.cn
• Phone: +8656119530

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.