Virtual reality training for people with opioid use disorder

Digital Therapeutic Development of Virtual Cognitive-Affective Training for Opioid Use Disorder: A Phase 2 Randomized Controlled Trial

Not applicable Interventional BehaVR LLC · NCT06021431

This study tests if a virtual reality program can help people with opioid use disorder reduce their cravings and opioid use while they receive their usual treatment.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment128 (estimated)
Ages18 Years and up
SexAll
SponsorBehaVR LLC Industry-sponsored
Locations1 site (Salt Lake City, Utah)
Trial IDNCT06021431 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effectiveness of a virtual reality intervention called Mindfulness-Oriented Recovery Enhancement in Virtual Reality (MORE-VR) for individuals diagnosed with opioid use disorder who are already receiving medication. Participants will be randomly assigned to either receive MORE-VR alongside their usual treatment or continue with treatment as usual. The study aims to measure the impact of MORE-VR on the number of days participants use opioids, as well as their drug cravings and mood, at the end of treatment and three months later.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who have a current diagnosis of opioid use disorder and are prescribed medication for their condition.

Not a fit: Patients who have previously completed a standardized mindfulness intervention or those with conditions contraindicated for virtual reality use may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly reduce opioid use and improve recovery outcomes for patients with opioid use disorder.

How similar studies have performed: While the use of virtual reality in therapeutic settings is emerging, this specific approach has not been widely tested, making it a novel intervention.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years of age or older
* current DSM-5 OUD diagnosis
* prescribed medications for opioid use disorder (e.g., buprenorphine, methadone)

Exclusion Criteria:

* completion of a standardized mindfulness intervention (e.g., MORE, MBRP, MBSR)
* active psychosis or suicidality
* reports, or is noted by clinical or study staff as showing cognitive impairment
* condition which might be contraindicated for VR use including seizure disorder, vertigo, severe motion sickness, recent concussion

Where this trial is running

Salt Lake City, Utah

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Opioid Use DisorderMindfulnessVirtual Reality
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.