Virtual reality exercise versus Mulligan mobilization for shoulder posture and function in subacromial impingement
Official title: Virtual Reality Based Exercise Training Versus Mulligan Mobilization on Shoulder Posture and Function in Subacromial Impingement Syndrome
Run by Cairo University · NCT07369934 · Data updated 2026-11-12
This trial will test whether virtual reality–based exercises or Mulligan mobilization, each added to exercise therapy, better improve shoulder posture and function in adults aged 30–50 with subacromial impingement syndrome.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 30 Years to 50 Years |
| Sex | All |
| Enrollment | 74 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Giza) |
| Status | Recruiting |
| Started | December 13, 2025 |
| Main results expected | May 2026 |
| Study ends | May 2026 |
| Registry record updated | January 27, 2026 |
| Trial ID | NCT07369934 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are non-athlete adults aged 30–50 with unilateral stage II subacromial impingement confirmed by specific clinical tests, BMI 18.5–29.9 kg/m², and no recent shoulder physical therapy or surgery.
✕Probably not a fit
Patients who recently had shoulder treatment or surgery, those with acute flares, malignancy, epilepsy, pregnancy, systemic illnesses, or BMI outside the specified range are unlikely to qualify or benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults with unilateral stage II subacromial impingement will be enrolled at the Faculty of Physical Therapy, Cairo University and assigned to receive either virtual reality–based exercise training or Mulligan mobilization, with exercise therapy provided to both groups. Baseline and follow-up measures of shoulder posture and functional outcomes will be collected to compare the two approaches. Inclusion criteria include age 30–50, non-athletes, specific positive impingement tests, unilateral pain, and BMI 18.5–29.9 kg/m², while recent shoulder treatment, prior tendon repair surgery, malignancy, epilepsy, pregnancy, or systemic conditions are excluded. Treatments are delivered in person at the study site and outcome changes will be analyzed between the groups.
Why it matters
Potential benefit: If successful, the approach that performs better could offer a non-surgical way to reduce pain and improve shoulder posture and function for people with subacromial impingement.
How similar studies have gone: Previous small trials and reviews have reported that both virtual reality rehabilitation and Mulligan mobilization can improve shoulder pain and function, but direct head-to-head comparisons are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients will be referred from the orthopedic surgeon with a diagnosis of stage II SIS with the following criteria: 1. Participants ranged in age from 30-50 years old. 2. Participants are from non-athletes from the general population. 3. Unilateral shoulder pain that is localized either anteriorly or laterally to the acromion. Pain that occurs or worsens when the affected shoulder is in flexion and/or abduction. 4. Four of the following should be present in the included patients: Neer impingement test, Hawkins' test, Pain was replicated in the supraspinatus empty-can test, a painful arc of movement from 70° to 120°, and painful greater tuberosity of the humerus. 5. BMI range 18.5- 29.9 Kg/m². Exclusion Criteria: * 1\) Patients who, during the previous three months, underwent shoulder physical treatment and/or an acute pain flare. 2\) Patients who have undergone surgeries for tendon repair. 3) Malignancy, epilepsy, pregnant women, and/or systemic conditions like chronic renal or liver failure. 4\) Mini-Mental State Examination test (MMSE) (\< 24/30) to exclude cognitive impairment and/or significant vision impairment (if they couldn't read the introduction while wearing the Head Mounted Device (HMD). 5\) Corticosteroid injection during the last three months or used steroids chronically. 6\) Adhesive capsulitis, glenohumeral joint instability, Numbness or tingling of the upper limb, and/or full-thickness tear of the rotator cuff.
Where it's running
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Faculty of Physical Therapy, Cairo University
Giza, Egypt Recruiting
Study contacts
- Study coordinator: Sara M Meselhy, Demonstrator
- Email: sara.mohsen@cu.edu.eg
- Phone: +01222518092
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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In people with subacromial impingement, this study tests whether adding low-load blood flow restriction training or Pilates to standard therapy helps reduce pain and improve shoulder function.
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This trial will test whether supervised physiotherapy or a home exercise program works better for adults aged 30–65 with unilateral subacromial impingement syndrome.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.