Clinical trial Recruiting at 1 site Interventional Ages 18 Weeks to 55 Weeks

Blood Flow Restriction Training vs Pilates for Subacromial Impingement

Official title: Blood Flow Restriction Versus Pilates Exercises in Treatment of Patients With Subacromial Impingement Syndrome

Run by Cairo University · NCT07608809 · Data updated 2026-11-12

In people with subacromial impingement, this study tests whether adding low-load blood flow restriction training or Pilates to standard therapy helps reduce pain and improve shoulder function.

Quick facts

Study typeInterventional
Ages18 Weeks to 55 Weeks
SexAll
Enrollment48 (estimated)
SponsorCairo University
Academic / other
Locations1 site (Rāshid)
StatusRecruiting
StartedMay 23, 2026
Main results expectedDecember 15, 2026
Study endsJanuary 15, 2027
Registry record updatedMay 27, 2026
Trial IDNCT07608809 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18–55 with clinically diagnosed subacromial impingement and 4–12 weeks of symptoms, who experience moderate pain (VAS 3–8) and can participate in low-load exercise.

Probably not a fit

Patients with full-thickness rotator cuff tears, recent shoulder surgery, acute impingement, or contraindications to exercise may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares two low-load exercise approaches—blood flow restriction training (BFR) and Pilates—to conventional therapy for subacromial impingement syndrome. Participants receive either BFR-based strengthening or Pilates in addition to standard rehabilitation, with the aim of improving pain, range of motion, and shoulder strength. The trial targets adults aged 18–55 with subacromial impingement symptoms lasting 4–12 weeks and moderate pain. Outcomes focus on pain levels, functional scores, and shoulder mobility to determine which approach offers better short- to mid-term benefits.

Why it matters

Potential benefit: If successful, the study could identify a more tolerable, effective way to restore shoulder function and reduce pain during rehabilitation.

How similar studies have gone: Previous research suggests potential benefits of both BFR and targeted rehabilitation exercises, but direct comparisons in SAIS are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1 - Age ranging from 18 to 55 years of both genders, with BMI ranging 18.5 to 29.9 Kg/m2 2. Clinically diagnosed with SIS, based on having ≥ 3 positive results of the following; pain during shoulder elevation and overhead activities, the painful arc, Neer impingement, Hawkins-Kennedy impingement, external rotation resistance, or empty can tests 3. Symptoms duration between 4 to 12 weeks (subacute and chronic phases)

4\. pain level should be ranged from 3 to 8 on the VAS .

Exclusion Criteria:

1 - History of shoulder surgery, traumatic injury or systematic diseases 2. Any cervical problems as cervical disc \& any patient with radioculopathy. 3. Pregnancy. 4. Acute stage of subacromial impingement syndrome 5. Full thickness tear confirmed by the orthopaedist. 6. subjects shouldn't receive any physical therapy sessions in the past 3 months to minimize any confounders to treatment.

Where it's running

  • Faculty of physical therapy, Rashid university
    Rāshid, Egypt
    Recruiting

Study contacts

  • Principal investigator: Enas Fawzy Youssf, Professor of physical therapy — Cairo University
  • Study coordinator: Manar Tarek Abdelnaser, Demonstrator
  • Email: tm610587@gmail.com
  • Phone: +2001553437534

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.