Clinical trial Recruiting at 1 site Interventional Ages 20 to 40

Mulligan Mobilization vs. PNF for Subacromial Impingement Syndrome

Official title: Shoulder Mulligan Mobilization Versus Proprioceptive Neuromuscular Facilitation Technique In Subacromial Impingement Syndrome

Run by Cairo University · NCT07675655 · Data updated 2026-11-12

This trial tests whether adding Mulligan mobilization or proprioceptive neuromuscular facilitation to standard physical therapy helps adults with Subacromial Impingement Syndrome.

Quick facts

Study typeInterventional
Ages20 Years to 40 Years
SexAll
Enrollment69 (estimated)
SponsorCairo University
Academic / other
Locations1 site (Sohag, Tahta)
StatusRecruiting
StartedSeptember 2, 2025
Main results expectedAugust 1, 2026
Study endsAugust 1, 2026
Registry record updatedJune 30, 2026
Trial IDNCT07675655 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 20–40 with clinically diagnosed SIS and a history of shoulder pain for more than one week who meet specific test criteria.

Probably not a fit

Patients with contraindications listed or those not responding to the added manual therapy may not experience additional benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares two manual therapy approaches plus standard therapy for SIS. Participants receive either Mulligan mobilization plus standard care or PNF plus standard care, or standard care alone, to see how these approaches affect shoulder pain, function, strength, range of motion, and scapular alignment. The trial focuses on adults aged 20–40 with SIS and specific clinical criteria, excluding those with recent surgery, severe comorbidities, or full-thickness rotator cuff tears. Outcomes include pain levels, functional measurements, and joint mobility to determine if one approach provides additional benefits beyond standard therapy. The study is led by Cairo University with collaboration at Magdy Eshak in Sohag and Tahta.

Why it matters

Potential benefit: If successful, patients with SIS could experience greater pain relief and improved shoulder function with targeted manual therapy.

How similar studies have gone: Previous research has explored manual therapy approaches for SIS, with varying levels of evidence supporting benefit from techniques like Mulligan mobilization and PNF.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Sixty nine Males and females subjects with SIS, age between 20-40 years old and body mass index (BMI) 18-27.9 kg/m2
2. The SIS group will be limited to patients who had history of shoulder pain of \>1-week duration.
3. Pain localized at the proximal anterolateral shoulder region.
4. Patients with subacromial pain syndrome with positive results of 3 of 5 tests: painful arc, pain or weakness with resisted external rotation, Neer test, Hawkins Kennedy test, and Jobe/empty can test.

Exclusion Criteria:

* Patients will be excluded if they had any of the following conditions:

  1. Open wounds, infection, acute injuries, swelling, rheumatoid arthritis, reflex sympathetic syndrome, or adhesive capsulitis.
  2. BMI greater than 28 kg/m².
  3. History of shoulder girdle fractures and dislocation, shoulder surgery in the last 12 months or full thickness rotator cuff tear.
  4. History of systemic or neurological disorder, cervical radiculopathy and subjects who had received physical therapy treatment for their shoulder within the past three months.
  5. History of corticosteroid injection in the shoulder region less than 12 weeks previously.

Where it's running

  • Magdy Eshak
    Sohag, Tahta, Egypt
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.