Mulligan Mobilization vs. PNF for Subacromial Impingement Syndrome
Official title: Shoulder Mulligan Mobilization Versus Proprioceptive Neuromuscular Facilitation Technique In Subacromial Impingement Syndrome
Run by Cairo University · NCT07675655 · Data updated 2026-11-12
This trial tests whether adding Mulligan mobilization or proprioceptive neuromuscular facilitation to standard physical therapy helps adults with Subacromial Impingement Syndrome.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 40 Years |
| Sex | All |
| Enrollment | 69 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Sohag, Tahta) |
| Status | Recruiting |
| Started | September 2, 2025 |
| Main results expected | August 1, 2026 |
| Study ends | August 1, 2026 |
| Registry record updated | June 30, 2026 |
| Trial ID | NCT07675655 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 20–40 with clinically diagnosed SIS and a history of shoulder pain for more than one week who meet specific test criteria.
✕Probably not a fit
Patients with contraindications listed or those not responding to the added manual therapy may not experience additional benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares two manual therapy approaches plus standard therapy for SIS. Participants receive either Mulligan mobilization plus standard care or PNF plus standard care, or standard care alone, to see how these approaches affect shoulder pain, function, strength, range of motion, and scapular alignment. The trial focuses on adults aged 20–40 with SIS and specific clinical criteria, excluding those with recent surgery, severe comorbidities, or full-thickness rotator cuff tears. Outcomes include pain levels, functional measurements, and joint mobility to determine if one approach provides additional benefits beyond standard therapy. The study is led by Cairo University with collaboration at Magdy Eshak in Sohag and Tahta.
Why it matters
Potential benefit: If successful, patients with SIS could experience greater pain relief and improved shoulder function with targeted manual therapy.
How similar studies have gone: Previous research has explored manual therapy approaches for SIS, with varying levels of evidence supporting benefit from techniques like Mulligan mobilization and PNF.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Sixty nine Males and females subjects with SIS, age between 20-40 years old and body mass index (BMI) 18-27.9 kg/m2 2. The SIS group will be limited to patients who had history of shoulder pain of \>1-week duration. 3. Pain localized at the proximal anterolateral shoulder region. 4. Patients with subacromial pain syndrome with positive results of 3 of 5 tests: painful arc, pain or weakness with resisted external rotation, Neer test, Hawkins Kennedy test, and Jobe/empty can test. Exclusion Criteria: * Patients will be excluded if they had any of the following conditions: 1. Open wounds, infection, acute injuries, swelling, rheumatoid arthritis, reflex sympathetic syndrome, or adhesive capsulitis. 2. BMI greater than 28 kg/m². 3. History of shoulder girdle fractures and dislocation, shoulder surgery in the last 12 months or full thickness rotator cuff tear. 4. History of systemic or neurological disorder, cervical radiculopathy and subjects who had received physical therapy treatment for their shoulder within the past three months. 5. History of corticosteroid injection in the shoulder region less than 12 weeks previously.
Where it's running
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Magdy Eshak
Sohag, Tahta, Egypt Recruiting
Study contacts
- Study coordinator: Mina Magdy, Master
- Email: mina.magdy.9595@gmail.com
- Phone: 01277660470
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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This trial will test whether supervised physiotherapy or a home exercise program works better for adults aged 30–65 with unilateral subacromial impingement syndrome.
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This trial will test whether virtual reality–based exercises or Mulligan mobilization, each added to exercise therapy, better improve shoulder posture and function in adults aged 30–50 with subacromial impingement syndrome.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.