Vibration plus electrical stimulation to improve ankle lifting after subacute ischemic stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional, single-center study enrolls subacute ischemic stroke patients and applies focal vibration to the ankle dorsiflexors either alone or combined with neuromuscular electrical stimulation (NMES). Participants are assigned to one of two intervention groups: segmental vibrator only or segmental vibrator plus electrical stimulation, with treatment sessions delivered in-person. Outcomes focus on ankle dorsiflexion, lower-limb motor function (including measures such as Fugl-Meyer scores), and related mobility measures over the treatment and follow-up period. The trial targets adults 45–60 years old who are 15 days to 12 weeks post-ischemic stroke and meet cognitive and spasticity eligibility criteria and is conducted at Jinnah Hospital in Lahore.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Both male and female patients were included in the study.
* The age range of participants was between 45 and 60 years.
* Participants that were diagnosed with ischemic stroke patient.
* Participants had experienced sub-acute ischemic stroke, specifically 15 days to 12 weeks post-stroke.
* Montreal Cognitive Assessment scores falling within the range of 18-24 were necessary.
* Modified Ashworth scale scores had to be less than +1
* National Institutes of Health Stroke Scale (NIHSS) score falling within the range of 1 to 15 were necessary.
* Participants feel no pain from the vibrator.
* It was anticipated that participants would either be able to give informed consent or have a legal representative who could do so.

Exclusion Criteria:

* People who had a history of serious neurological or mental conditions that would have impeded lower limb motor recovery-aside from stroke-were not included.
* Individuals with severe arthritis or joint injuries, among other illnesses that would have interfered with treatment or evaluations, were not allowed to participate.
* Individuals who had significant hearing or vision impairments that would have hampered treatment or evaluations were not included.
* Individuals undergoing anti-spatial therapy or other clinical trials, those with bilateral brain lesions, and those with ischemic involvement of the cerebellum or basal ganglia were not allowed to participate.
* Participants having metal implants e. g cardiac pacemaker and skin lesion at the site of stimulation electrodes were excluded.

Where it's running

• Jinnah Hospital
  Lahore, Punjab Province, Pakistan Recruiting

Study contacts

• Principal investigator: Aruba Saeed, PhD — Riphah International University
• Study coordinator: Aruba Saeed, Phd
• Email: arubasaeedpt@gmail.com
• Phone: 03344399403

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.