Clinical trial Recruiting at 1 site Observational Ages 18 and up

Ventilator-associated pneumonia rates and use of SRLF 2017 diagnostic rules in an ICU (2022–2024)

Official title: VAP Incidence and Adequation to SRLF 2017 Diagnostic Among an Intensive Care Medicine Service for the Period 2022 à 2024

Run by Centre Hospitalier Sud Francilien · NCT07181824 · Data updated 2026-11-12

This project will look at respiratory samples from adults on mechanical ventilation in a regional ICU to see if doctors followed the SRLF 2017 rules when diagnosing ventilator-associated pneumonia between 2022 and 2024.

More Ventilator Associated Pneumonia trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment100 (estimated)
SponsorCentre Hospitalier Sud Francilien
Academic / other
Locations1 site (Corbeil-Essonnes, France)
StatusRecruiting
StartedAugust 25, 2025
Main results expectedJune 30, 2026
Study endsJune 30, 2026
Registry record updatedDecember 9, 2025
Trial IDNCT07181824 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18 or older who were admitted to the Centre Hospitalier Sud Francilien ICU between 01/01/2022 and 12/31/2024, were intubated and mechanically ventilated for more than 48 hours, and had a positive respiratory sample.

Probably not a fit

Organ donors, patients with a decision to limit therapy, and patients who refuse participation are excluded and will not be included or benefit from the review.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a retrospective observational review of respiratory samples and clinical records from mechanically ventilated adult patients cared for in a single regional ICU between January 1, 2022 and December 31, 2024. Patients included are adults intubated and ventilated for more than 48 hours with a positive respiratory sample, excluding organ donors and patients with therapeutic limitation decisions. Clinical and radiological data will be compared to the 2017 SRLF diagnostic criteria to determine whether those criteria were applied and to measure VAP incidence in this population. Results will include adherence rates to SRLF guidance, patterns of microbiology, and descriptive information on antibiotic use and ventilation duration.

Why it matters

Potential benefit: If successful, the findings could help improve local diagnosis of VAP, reduce unnecessary antibiotic use, and inform targeted infection-control measures.

How similar studies have gone: Previous retrospective analyses using ATS/IDSA or SRLF diagnostic criteria have reported variable adherence and incidence estimates, so the approach is established but results vary by center.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults ≥ 18 years
* Hospitalization in Intensive care unit for the period between 01/01/2022 and 31/12/2024
* Intubation and mechanical ventilation for \> 48h
* Positive respiratory sample

Exclusion Criteria:

* Decision of therapeutic limitation
* Organ donors
* Patient refuse to participate

Where it's running

  • Centre Hospitalier Sud Francilien
    Corbeil-Essonnes, France, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.