Ventilator-associated pneumonia rates and use of SRLF 2017 diagnostic rules in an ICU (2022–2024)
VAP Incidence and Adequation to SRLF 2017 Diagnostic Among an Intensive Care Medicine Service for the Period 2022 à 2024
Centre Hospitalier Sud Francilien · NCT07181824
This project will look at respiratory samples from adults on mechanical ventilation in a regional ICU to see if doctors followed the SRLF 2017 rules when diagnosing ventilator-associated pneumonia between 2022 and 2024.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Sud Francilien (other) |
| Locations | 1 site (Corbeil-Essonnes, France) |
| Trial ID | NCT07181824 on ClinicalTrials.gov |
What this trial studies
This is a retrospective observational review of respiratory samples and clinical records from mechanically ventilated adult patients cared for in a single regional ICU between January 1, 2022 and December 31, 2024. Patients included are adults intubated and ventilated for more than 48 hours with a positive respiratory sample, excluding organ donors and patients with therapeutic limitation decisions. Clinical and radiological data will be compared to the 2017 SRLF diagnostic criteria to determine whether those criteria were applied and to measure VAP incidence in this population. Results will include adherence rates to SRLF guidance, patterns of microbiology, and descriptive information on antibiotic use and ventilation duration.
Who should consider this trial
Good fit: Adults aged 18 or older who were admitted to the Centre Hospitalier Sud Francilien ICU between 01/01/2022 and 12/31/2024, were intubated and mechanically ventilated for more than 48 hours, and had a positive respiratory sample.
Not a fit: Organ donors, patients with a decision to limit therapy, and patients who refuse participation are excluded and will not be included or benefit from the review.
Why it matters
Potential benefit: If successful, the findings could help improve local diagnosis of VAP, reduce unnecessary antibiotic use, and inform targeted infection-control measures.
How similar studies have performed: Previous retrospective analyses using ATS/IDSA or SRLF diagnostic criteria have reported variable adherence and incidence estimates, so the approach is established but results vary by center.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults ≥ 18 years * Hospitalization in Intensive care unit for the period between 01/01/2022 and 31/12/2024 * Intubation and mechanical ventilation for \> 48h * Positive respiratory sample Exclusion Criteria: * Decision of therapeutic limitation * Organ donors * Patient refuse to participate
Where this trial is running
Corbeil-Essonnes, France
- Centre Hospitalier Sud Francilien — Corbeil-Essonnes, France, France (RECRUITING)
Study contacts
- Principal investigator: Luis ENSENYAT MARTIN, MD — Centre Hospitalier Sud Francilien
- Study coordinator: Luis ENSENYAT MARTIN, MD
- Email: luis.ensenyatmartin@chsf.fr
- Phone: 33 1 61 69 31 57
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Pneumonia Ventilator Associated, Ventilatory associated pneumonia, VAP, Intensive Care medicine, Mechanical ventilation, Pneumonia