Velocity-Loss Resistance Training in Parkinson's Disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares two velocity-loss resistance training protocols at 10% and 30% thresholds in adults with Parkinson's disease. Outcomes focus on changes in muscle strength, power, and performance in daily activities. The trial uses a controlled intervention design conducted in a university lab setting to gauge functional benefits and safety. Eligible participants are diagnosed with Parkinson's disease, Hoehn and Yahr stages 1–3, who can walk 50 meters and communicate in English. Exclusion criteria include uncontrolled cardiovascular or other neuromuscular conditions, inflammatory or autoimmune diseases, or limb injuries limiting weight training.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Parkinson's Disease Hoehn \& Yahr Stages 1-3
* Able to walk 50 meters unassisted
* Able to understand and communicate in English

Exclusion Criteria:

* Uncontrolled cardiovascular or other neuromuscular disease that prevent participation in a training program
* Any systemic inflammatory or autoimmune conditions such as rheumatoid arthritis, or other serious concomitant medical illness
* Unresolved injury or surgery to the upper or lower limbs that prevents weight training.

Where it's running

• Laboratory of Neruomuscular Research and Active Aging
  Coral Gables, Florida, United States Recruiting

Study contacts

• Principal investigator: Joseph F. Signorile, PhD — University of Miami - Coral Gables Campus
• Study coordinator: Ethan A Elkins, MS
• Email: exe453@miami.edu
• Phone: 3052844173

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.