Validation of hematological indices in cardiac surgery patients
Official title: Validation of Hematological Indices as Prognostic Markers of Inflammatory Complications and Multiple Organ Dysfunction in Cardiac Surgery Patients.
Run by Petrovsky National Research Centre of Surgery · NCT06476171 · Data updated 2026-11-12
This study is testing if certain blood test results can help predict infections and organ problems in patients who are having heart surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Petrovsky National Research Centre of Surgery Academic / other |
| Locations | 1 site (Moscow) |
| Status | Recruiting |
| Started | June 19, 2023 |
| Main results expected | November 1, 2025 |
| Study ends | December 30, 2025 |
| Registry record updated | November 25, 2024 |
| Trial ID | NCT06476171 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 to 80 who are scheduled for cardiac surgery involving cardiopulmonary bypass.
✕Probably not a fit
Patients who refuse to participate or are transferred to another medical institution may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to validate hematological indices, such as the neutrophil to lymphocyte ratio and platelet to lymphocyte ratio, as potential predictors of infectious complications and multiple organ dysfunction in patients undergoing cardiac surgery. It is a single-center interventional prospective study involving 200 patients, where blood samples will be collected at three stages: before surgery, on the first day after surgery, and on the third day after surgery. The study will analyze these indices alongside other biomarkers to determine their effectiveness in predicting postoperative complications. Patients will be monitored throughout their hospital stay, and data will be statistically analyzed to identify correlations between hematological indices and patient outcomes.
Why it matters
Potential benefit: If successful, this study could improve the prediction and management of postoperative complications in cardiac surgery patients.
How similar studies have gone: Other studies have shown promise in using hematological indices as predictors of complications, suggesting this approach may be beneficial.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * age from 18 to 80 years * cardiac surgery * operation in the conditions of cardiopulmonary bypass * availability of voluntary informed consent of the patient to participate in the study Exclusion Criteria: * refusal of the patient from the study * transfer of the patient to another medical institution
Where it's running
-
Petrovsky National Reasearch Centre of Surgery
Moscow, Russia Recruiting
Study contacts
- Principal investigator: Maxim A. Babaev, D.M. — Petrovsky NRCS
- Study coordinator: Maxim A. Babaev, D.M.
- Email: maxbabaev@mail.ru
- Phone: 89160269066
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.