Validation of hematological indices in cardiac surgery patients
Validation of Hematological Indices as Prognostic Markers of Inflammatory Complications and Multiple Organ Dysfunction in Cardiac Surgery Patients.
This study is testing if certain blood test results can help predict infections and organ problems in patients who are having heart surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Petrovsky National Research Centre of Surgery Academic / other |
| Locations | 1 site (Moscow) |
| Trial ID | NCT06476171 on ClinicalTrials.gov |
What this trial studies
This study aims to validate hematological indices, such as the neutrophil to lymphocyte ratio and platelet to lymphocyte ratio, as potential predictors of infectious complications and multiple organ dysfunction in patients undergoing cardiac surgery. It is a single-center interventional prospective study involving 200 patients, where blood samples will be collected at three stages: before surgery, on the first day after surgery, and on the third day after surgery. The study will analyze these indices alongside other biomarkers to determine their effectiveness in predicting postoperative complications. Patients will be monitored throughout their hospital stay, and data will be statistically analyzed to identify correlations between hematological indices and patient outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 to 80 who are scheduled for cardiac surgery involving cardiopulmonary bypass.
Not a fit: Patients who refuse to participate or are transferred to another medical institution may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the prediction and management of postoperative complications in cardiac surgery patients.
How similar studies have performed: Other studies have shown promise in using hematological indices as predictors of complications, suggesting this approach may be beneficial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * age from 18 to 80 years * cardiac surgery * operation in the conditions of cardiopulmonary bypass * availability of voluntary informed consent of the patient to participate in the study Exclusion Criteria: * refusal of the patient from the study * transfer of the patient to another medical institution
Where this trial is running
Moscow
- Petrovsky National Reasearch Centre of Surgery — Moscow, Russia (Recruiting)
Study contacts
- Principal investigator: Maxim A. Babaev, D.M. — Petrovsky NRCS
- Study coordinator: Maxim A. Babaev, D.M.
- Email: maxbabaev@mail.ru
- Phone: 89160269066
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.