Validation of a survival prediction tool for metastatic cancer patients receiving palliative radiation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to validate a survival prediction tool developed by Lee et al. for patients with metastatic cancer referred to radiation oncology for palliative treatments. Patients will be assigned a survival score based on objective data such as laboratory values and emergency room visits at the time of enrollment. The score ranges from 0 to 20, categorizing patients into low, intermediate, and high-risk groups based on their prognosis. Patient survival and quality of life will be monitored at 30, 90, and 365 days post-enrollment to evaluate the tool's effectiveness.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age ≥ 18 at time of consent
2. Ability to provide written informed consent
3. Cancer diagnosis referred to Radiation Oncology for palliative radiation therapy
4. Patients who either choose to not receive radiation therapy or not recommended to receive radiation therapy will remain eligible
5. Those patients who undergo a course of palliative radiation therapy, it is not the requirement of this study to complete that course of treatment. Those who prematurely end their course of treatment will remain eligible Note: Patients who ultimately either choose to not receive radiation or not recommended to receive radiation will remain eligible

Note: Patients who ultimately do not complete prescribed radiation will remain eligible

Exclusion Criteria:

1. Patients who are unable to participate in follow up visits per investigator discretion (virtual/phone follow up is permitted)
2. Patients who are receiving definitive/curative course of radiation therapy
3. Patients who self-report as pregnant or nursing

Where it's running

• IU Health West
  Avon, Indiana, United States Recruiting
• IU Health North / Schwarz Cancer Center
  Carmel, Indiana, United States Recruiting
• Methodist Hospital
  Indianapolis, Indiana, United States Recruiting

Study contacts

• Principal investigator: Naoyuki Saito, MD PhD — Indiana University
• Study coordinator: Jessica Anders
• Email: jemlynn@iu.edu
• Phone: (317) 274-0220

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.