Validation of a management algorithm for heart conduction issues after TAVR

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to validate a pre-specified algorithm designed to manage conduction disturbances that occur following transcatheter aortic valve replacement (TAVR). It will assess the feasibility and efficacy of this algorithm by monitoring the rate of permanent pacemaker implantation and the incidence of sudden death in patients undergoing TAVR. By applying this standardized approach to a large cohort, the study seeks to improve clinical outcomes and reduce variability in treatment practices. The findings may provide insights into the best management strategies for patients experiencing these complications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

-Patients with aortic valve disease undergoing transcatheter aortic valve replacement

Exclusion Criteria:

* Prior permanent pacemaker
* Failure to provide signed informed consent for data collection
* Impossibility for a follow-up
* Unwillingness to follow the pre-specified strategy for the management of conduction disturbances

Where it's running

• Iucpq
  Québec, Quebec, Canada Recruiting

Study contacts

• Study coordinator: Josep Rodes-Cabau, MD
• Email: josep.rodes@criucpq.ulaval.ca
• Phone: 418-656-8711

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• SYMmetric Valve expansion to reduce hypoattenuated leaflet thickening after balloon-expandable TAVI

  This trial tests whether the Double-TAP post-dilatation strategy can reduce HALT and improve valve function in patients 70 or older undergoing balloon-expandable TAVI.

  Recruiting Erasmus Medical Center · Düsseldorf and 4 other locations · NCT07872020

• Systematic 14-day ambulatory heart monitoring after TAVI

  After TAVI, patients with certain heart conduction abnormalities will try 14 days of wearable ECG monitoring to see if it lowers the chances of sudden death, symptomatic heart rhythm problems, or stroke within a year compared to standard follow-up.

  Recruiting Institut universitaire de cardiologie et de pneumologie de Québec, University Laval · Québec, Quebec · NCT07739316

• Low-dose Colchicine after TAVR to help prevent valve clots

  This study tests whether taking a low dose of colchicine for 12 months after transcatheter aortic valve replacement can reduce valve thrombosis compared with standard care alone.

  Recruiting China National Center for Cardiovascular Diseases · Beijing · NCT07411768

• Transcatheter Mitral and Tricuspid Interventions and Cardiac MRI Registry

  This study will collect imaging and clinical data from adults undergoing transcatheter mitral or tricuspid procedures to see how their heart structure and function change over time using MRI and advanced ultrasound.

  Recruiting Centro Cardiologico Monzino · Milan, Milan · NCT07370467

• Using blood markers to predict conduction problems after TAVI

  This study will test whether blood levels of inflammation and fibrosis markers taken before TAVI can help predict which patients with severe aortic stenosis will develop new conduction problems or need a permanent pacemaker.

  Recruiting Clinical Hospital Center Rijeka · Rijeka, Croatia · NCT07201363

• Evaluation of the Point-Guard device during heart valve replacement

  This study is testing a new device called Point-Guard to see if it can help prevent brain problems during heart valve replacement surgery.

  Recruiting Transverse Medical, Inc. · Clayton, Victoria · NCT06962371

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.