Using urine to study immune responses to chlamydia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study explores non-invasive samples collected by participants to detect mucosal and systemic immune responses to Chlamydia trachomatis. Researchers will compare CT-specific antibodies and cellular responses in urine and vaginal samples with blood samples, aiming to assess feasibility and concordance. The study also investigates how local genital tract immunity relates to systemic immunity. Eligible participants are adult women with CT-positive samples who consent to self-collection and an in-clinic blood draw and questionnaire completion.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female
* Chlamydia trachomatis NAAT positive vaginal sample or first-void urine sample.
* Able to understand the information brochure and what the study is about.
* Willing to give informed consent to use their samples for details described in the study protocol.

Exclusion Criteria:

* Pregnancy (self-reported)
* Being positive for Human Immunodeficiency Virus (HIV)
* Women that underwent hysterectomy.
* Menstruation at the time of sample collection.
* Current use of antibiotics effective against Chlamydia trachomatis (doxycyline or azithromycine) or use of such antimicrobials in the past 14 days before participating in the study.
* Participating in another clinical trial at the same time of participating in this study.
* Having a history or current evidence of any condition or abnormality that might confound the results of the study or is not in the best interest of the individual to participate, in the opinion of the investigator.

Where it's running

• Violett Antwerp
  Antwerp, Antwerp, Belgium Recruiting

Study contacts

• Study coordinator: Anne Van Caesbroeck
• Email: anne.vancaesbroeck@uantwerpen.be
• Phone: +32 476 01 48 43

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.