Using ultrasound to measure muscle mass in older women with gynecologic cancer to predict hospital stay length
Measuring Ultrasound Guided Skeletal Muscle Mass of Lower Extremity as a Predictor of Post-Operative Length of Stay in Exploratory Gynae-oncology Surgeries
This study is testing if using ultrasound to measure muscle mass in older women with gynecologic cancer can help predict how long they will stay in the hospital after surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 320 (estimated) |
| Ages | 50 Years to 99 Years |
| Sex | Female |
| Sponsor | Tata Medical Center Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Kolkata, West Bengal) |
| Trial ID | NCT06816836 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the use of bedside ultrasound to measure skeletal muscle mass in the lower extremities of women over 50 years old undergoing open surgeries for gynecologic cancer. The focus is on determining whether this measurement can serve as a predictor for postoperative length of stay, particularly in patients with sarcopenia, a condition characterized by muscle loss and frailty. By recruiting 320 patients, the study will compare outcomes between those with and without sarcopenia, collecting relevant data alongside muscle mass measurements. This approach seeks to provide a less invasive and more efficient alternative to traditional frailty assessments.
Who should consider this trial
Good fit: Ideal candidates are women over 50 years old with a Charlson Comorbidity Index score of 3 or more, undergoing open surgeries for gynecologic cancer.
Not a fit: Patients under 50 years old, those with psychiatric illnesses, neuromuscular disorders, or previous major limb surgeries may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved postoperative care and reduced hospital stays for older women undergoing gynecologic surgeries.
How similar studies have performed: While the use of ultrasound for muscle mass measurement is gaining traction, this specific application in predicting postoperative outcomes in gynecologic cancer patients is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All consecutive consenting patients above 50 years of age, having a Charlson Comorbidity Index score of 3 or more, undergoing open surgeries for GCs. Exclusion Criteria: A. Refusal of consent B. Patients with psychiatric illnesses who are unable to follow instructions. C. Patients below the age of 50 years. D. Patients with known neuromuscular disorders. E. Patients in whom contrast-enhanced CT scan of the abdomen and pelvis is not done. F. Previous major surgery of limbs (Amputation, Hip surgeries/ long bone surgeries)
Where this trial is running
Kolkata, West Bengal
- Tata Medical Center — Kolkata, West Bengal, India (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.