Using ultrasound to guide fluid therapy in preeclampsia patients before surgery
Ultrasound Assessment of Inferior Vena Cava Collapsibility Index (IVCCI) to Guide Pre-operative Fluid Management in Critically Ill Pre-eclamptic Patients in Comparison with the Standard Fluid Management
NA · Ain Shams University · NCT06539026
This study is testing if using ultrasound to check fluid levels can help doctors better manage fluids for pregnant women with preeclampsia during cesarean sections.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Sex | Female |
| Sponsor | Ain Shams University (other) |
| Locations | 1 site (Cairo, Egypt) |
| Trial ID | NCT06539026 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of using the Inferior Vena Cava Collapsibility Index (IVCCI) assessed through point-of-care ultrasound to guide fluid therapy in critically ill pre-eclamptic patients undergoing cesarean sections. The aim is to determine whether this ultrasound-guided approach can optimize fluid management, reducing the risks associated with both fluid overload and under-resuscitation. By comparing traditional fluid management strategies with IVCCI-guided therapy, the study seeks to provide evidence for a more objective and safer method of fluid assessment in this high-risk population.
Who should consider this trial
Good fit: Ideal candidates for this study are critically ill pre-eclamptic patients scheduled for cesarean section.
Not a fit: Patients with severe cardiovascular disease, contraindications for spinal anesthesia, or significant hepatic or renal dysfunction may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved fluid management in preeclamptic patients, potentially reducing maternal and fetal complications during cesarean sections.
How similar studies have performed: While some studies suggest the IVCCI can predict fluid responsiveness, this trial is novel as it specifically focuses on its application in the obstetric population.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Critically ill pre-eclamptic patients for cesarean section Exclusion Criteria: * Patient refusal * severe cardiovascular disease ( ejection fraction \< 40 mmHg ), tricuspid regurge. * contraindication for spinal anesthesia. * failure to perform spinal anesthesia. * severe hepatic. * renal dysfunction
Where this trial is running
Cairo, Egypt
- Ain shams university — Cairo, Egypt, Egypt (RECRUITING)
Study contacts
- Study coordinator: wessam selima, MD
- Email: w.z.selima@med.asu.edu.eg
- Phone: 01001958858
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Pre-Eclampsia, Hypotension, Fluid Overload