Using Systane COMPLETE to improve dry eye symptoms before and after cataract surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effects of Systane COMPLETE, a lipid-containing nano-emulsion artificial tear, on patients with dry eye undergoing cataract surgery. It compares corneal astigmatism data before and after the use of Systane COMPLETE to assess its impact on postoperative residual astigmatism. Additionally, the study measures preoperative and postoperative Ocular Surface Disease Index (OSDI) scores and Non-Invasive Tear Break-Up Time (NITBUT) to determine the effectiveness of the treatment in alleviating dry eye symptoms. The goal is to address the challenges posed by dry eye on surgical outcomes and patient comfort.

Why it matters

Who can join: the full rules

Inclusion Criteria (Experimental group ): Cataract patients who participated in the "Optimizing the Ocular Surface with Systane COMPLETE in Patients with Dry Eye Planning for Cataract Surgery" trial (Research Ethics Committee Approval Number: 202311109MIPD) and did not withdraw from the trial midway.

Exclusion Criteria (Experimental group ): Patients unwilling to participate in this trial after surgery.

Inclusion Criteria(Control group):

* Cataract patients aged between 20 and 85 years.
* Patients with normal cognitive function who are able to complete the dry eye questionnaire (with - responses recorded by the research team) and are willing to undergo phacoemulsification and intraocular lens implantation under topical anesthesia.

Exclusion Criteria (Control group):

* Unable to answer the questions in the dry eye survey.
* Ocular trauma or ocular surgery in the planned surgical eye, active ocular infection, and obvious abnormalities in ocular surface or eyelid margins other than MGD cause decreased visual acuity other than cataracts.
* Dry eye signs: Corneal Fluorescein Staining CFS (+) to exclude any corneal abnormalities or epithelial defect.
* Systemic drug use, including tetracycline derivatives, antihistamines, and isotretinoin.
* Using dry eye medication at screening stage.

Where it's running

• National Taiwan University Hospital
  Taipei, Taiwan Recruiting

Study contacts

• Principal investigator: Chiun Ho Hou, Ph.D — National Taiwan University Hospital
• Study coordinator: Chiun Ho Hou, Ph.D
• Email: chiunhohou@gmail.com
• Phone: +88623123456

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.