Using stereotactic radiosurgery to treat essential and Parkinsonian tremors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the impact of stereotactic radiosurgery (SRS) on the quality of life and severity of tremors in patients with essential tremor or Parkinsonian tremor. Participants will complete questionnaires to assess their experiences and outcomes following SRS treatment, which utilizes focused radiation to target the brain region responsible for tremors. The study seeks to determine if linear accelerator-based SRS is as effective and safe as the more commonly reported Gamma Knife procedures. This approach offers a noninvasive alternative for patients who are not candidates for traditional surgical options.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Must be certified by a neurologist as having essential tremor or Parkinsonian tremor that is insufficiently controlled by medication alone.
* Preference to receive radiation treatment for tremor treatment, rather than surgical DBS implantation or surgical thalamotomy
* At least 18 years old

Exclusion Criteria:

* Contraindications to cranial radiation (such as prior radiation to the thalamus)
* Inability to have a MRI of the brain
* Prior surgical thalamotomy treatment (but contralateral deep brain stimulator \[DBS\] is permitted)
* Estimated life expectancy less than 1 year

Where it's running

• Vanderbilt University Medical Center
  Nashville, Tennessee, United States Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.