Using SPECT/CT bone scans to identify candidates for lumbar surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of SPECT/CT bone scan quantification to identify patients who are likely to respond positively to lumbar arthrodesis surgery for chronic low back pain. It aims to improve preoperative assessments by incorporating advanced imaging techniques to better predict surgical outcomes. Participants will undergo a bone scan prior to surgery, and their responses will be evaluated using the Oswestry Disability Index and Numerical Pain Scale. The goal is to enhance patient selection for surgery and ultimately improve recovery outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Persons with back pain for at least 3 months (presumed to be due to degenerative disc disease or spondylolisthesis).
* Persons who have received full information about the organisation of the research and have signed the informed consent and :

  * Age ≥ 18 years, having read and understood the information document.
  * Affiliated to a social security scheme.
* Lumbar arthrodesis involving a maximum of 2 floors.
* Standardized lumbar arthrodesis surgery performed by one of the three senior neurosurgeons of the neurosurgery department of the Nancy CHRU, using similar surgical techniques.

Exclusion Criteria:

* Low back pain of neuropathic origin. The Neuropathic Pain Scale 4 questionnaire is used to diagnose neuropathic pain (score is ≥ 4/10)
* History of lumbar spine surgery
* Presence of other pathologies responsible for lumbar pain (multistage discopathies, ankylosing spondylitis, spondylodiscitis, rheumatoid arthritis, vertebral compression, vertebral metastasis, narrow lumbar canal, scoliosis, spondylolisthesis by isthmic lysis)
* Pregnant women or women of childbearing age without suitable contraception or nursing mothers.
* Unstable medical condition and/or inability to remain immobile in supine position during recordings.
* Known allergy to any component of the radiopharmaceutical (TECHNESCAN HDP).
* Person referred to in Articles L. 1121-5, L. 1121-7 and L1121-8 of the Public Health Code.
* Persons deprived of their liberty by a judicial or administrative decision, persons under psychiatric care by virtue of Articles L. 3212-1 and L. 3213-1.
* Persons of full age who are unable to express their opposition.

Where it's running

• Nuclear Medicine Department
  Vandœuvre-lès-Nancy, France Recruiting

Study contacts

• Study coordinator: Achraf BAHLOUL, MD
• Email: a.bahloul@chru-nancy.fr
• Phone: 383153911

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.