Age-related changes in electrical properties measured by MRI
Official title: Imaging of Electrical Properties by MRI: Investigation of Age-Related Changes
Run by Central Hospital, Nancy, France · NCT07415759 · Data updated 2026-11-12
This study tests if MRI can map age-related differences in tissue electrical properties to improve MRI safety models for people of different ages.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 6 Years and up |
| Sex | All |
| Enrollment | 120 (estimated) |
| Sponsor | Central Hospital, Nancy, France Academic / other |
| Locations | 2 sites (Vandœuvre-lès-Nancy, CHRU de Nancy and 1 other locations) |
| Status | Recruiting |
| Started | April 4, 2026 |
| Main results expected | February 2, 2029 |
| Study ends | February 2, 2029 |
| Registry record updated | June 12, 2026 |
| Trial ID | NCT07415759 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Healthy individuals aged 6–12, 20–40, or 70 and older who are affiliated with a social security scheme and can provide informed consent (or parental/guardian consent for minors).
✕Probably not a fit
Individuals who do not fit the age ranges, lack MRI compatibility, or have conditions affecting MRI parameters may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Researchers will collect MRI-based maps of tissue electrical properties from participants in three age groups to build a searchable database. The goal is to improve SAR modeling and safety assessments by accounting for age, anatomy, and tissue complexity. The study uses a standard MRI examination to derive personalized EP values and compare them across age groups. It is designed as an interventional imaging protocol without a traditional therapeutic intervention. Participants will be healthy volunteers who meet inclusion criteria and provide informed consent.
Why it matters
Potential benefit: If successful, safer and more accurate MRI safety assessments could reduce unnecessary limitations and improve patient protection during scans.
How similar studies have gone: Prior work in MRI-based tissue property mapping has shown promise for safety modeling, though this exact age-stratified EP mapping approach is exploratory.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Person aged between 6 and 12, 20 and 40 years or aged 70 years and above * Person affiliated with a social security scheme or beneficiary of such a scheme * Person, or parent/legal guardian in the case of minors, who has received full information about the organization of the study and has signed the informed consent form Exclusion Criteria: * Contraindication to undergoing an MRI examination or the presence of an MRI-incompatible medical device * Person presenting a pathology or tissue damage in the examined areas that may affect the measured MRI parameters * Pregnant woman, woman in labor, or breastfeeding mother * Person deprived of liberty by judicial or administrative decision, or persons undergoing psychiatric care
Where it's running
-
CHRU Nancy
Vandœuvre-lès-Nancy, CHRU de Nancy, France Recruiting -
Institut de Physique Biologique
Strasbourg, France Recruiting
Study contacts
- Study coordinator: Marc BRAUN, MD, PhD
- Email: m.braun@chru-nancy.fr
- Phone: 0383157823
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Eating disorders in people with phenylketonuria
This study looks at whether eating disorders and BMI issues are more common in people with phenylketonuria who are followed at a French hospital.
-
Piperacillin Prophylaxis in Major Liver and Pancreatic Surgery
This study tests whether piperacillin/tazobactam given around surgery reliably reaches the right levels to help prevent infections in adults undergoing major liver or pancreatic surgery.
-
Real-time CLE imaging to speed and improve lung cancer diagnosis
This project will try to see if using confocal laser endomicroscopy (CLE) during bronchoscopic biopsy can diagnose non-small cell lung cancer faster and with fewer or safer biopsies for people with suspected lung tumors.
-
Comparing the 2024 and 2017 McDonald rules for diagnosing multiple sclerosis
This study will test whether the 2024 McDonald rules diagnose more people with MS at their first neurology visit than the 2017 rules for patients with a first clinical or radiological event suggestive of MS.
-
Sauna therapy added to cardiac rehab for heart failure with reduced or moderately reduced EF
In people with heart failure and reduced ejection fraction, this study tests whether adding sauna therapy to standard cardiac rehabilitation can reduce congestion and may allow lowering diuretic doses.
-
See if inflammation and scarring in Crohn's can be mapped from resected tissue
This study tests whether detailed ex vivo MRI and tissue measurements on Crohn’s tissue removed during surgery can reveal inflammation versus fibrosis to guide future treatments.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.