Using silver-coated prostheses to reduce hip infection rates

Clinical Investigation of the Efficacy of New Silver-coated Prosthesis in Reducing the Incidence of Periprosthetic Infections

Observational Istituto Ortopedico Rizzoli · NCT06887816

This study tests whether using silver-coated hip implants can help reduce infection rates in patients who are at high risk for infections during and after hip surgery.

Quick facts

Study typeObservational
Enrollment70 (estimated)
Ages18 Years and up
SexAll
SponsorIstituto Ortopedico Rizzoli Academic / other
Locations2 sites (Bologna, BO and 1 other locations)
Trial IDNCT06887816 on ClinicalTrials.gov

What this trial studies

This observational clinical investigation aims to evaluate the efficacy of a silver-coated prosthesis in reducing the incidence of periprosthetic infections during and after hip surgeries. The study focuses on patients at high risk for infections, including the elderly and those with underlying health conditions. By comparing outcomes between patients receiving the silver-coated device and those with a standard prosthesis, the research seeks to determine the effectiveness of the silver coating in preventing infections. The study will involve monitoring patients for both early and late postoperative infections.

Who should consider this trial

Good fit: Ideal candidates for this study include adults aged 18 and older who are immunocompromised or diabetic.

Not a fit: Patients under 18 years of age and pregnant women are unlikely to benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly lower the rates of infections following hip surgeries, leading to better patient outcomes and fewer revision surgeries.

How similar studies have performed: Previous studies have shown promising results with silver-coated devices in reducing infection rates, suggesting that this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged ≥ 18 years;
* Immunocompromised patients and/or diabetic patients.
* Patients who have given consent

Exclusion Criteria:

* Patients aged \< 18 years;
* Pregnant women;

Where this trial is running

Bologna, BO and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hip Infectionsilver coatingprimary prosthesissecond stage surgery
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.