Using saffron mouth rinse to treat periodontitis in patients with kidney disease

Clinical Efficacy of Saffron Mouth Rinse in Periodontitis Patients With Renal Disease: A Randomized Controlled Clinical Trial

Not applicable Interventional British University In Egypt · NCT06235021

This study is testing if using a saffron mouth rinse can help people with kidney disease who have gum problems feel better when combined with regular dental treatments.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment20 (estimated)
Ages19 Years and up
SexAll
SponsorBritish University In Egypt Academic / other
Locations1 site (Cairo)
Trial IDNCT06235021 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the efficacy of saffron mouth rinse as an adjunctive treatment for periodontitis in patients with renal disease. The study aims to address the limitations of standard periodontal treatments, such as scaling and root planning, by incorporating saffron, known for its anti-inflammatory and antibacterial properties. Participants will be assessed for their periodontal condition and treated with saffron mouth rinse alongside conventional therapies. The trial will evaluate the impact of this herbal intervention on periodontal inflammation and overall oral health.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 years old who have been diagnosed with periodontal disease and do not have any contraindications to the treatment.

Not a fit: Patients who smoke, consume alcohol, or belong to vulnerable groups such as pregnant women or those with known hypersensitivity to the treatment will not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could provide a natural and effective adjunct therapy for improving oral health in patients with periodontitis and renal disease.

How similar studies have performed: While the use of herbal treatments in periodontal therapy is gaining interest, the specific application of saffron mouth rinse for this purpose is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* - Both genders, aged above 18 years.
* All patients must have a periodontal disease.
* Patients must be able to make reliable decision or communications.

Exclusion Criteria:

* - Smoking, Alcohol.
* Vulnerable groups such as pregnant females, prisoners, mentally and physically handicapped individuals.
* Known hypersensitivity or severe adverse effects to the treatment drugs or to any ingredient of their preparation.

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Periodontal DiseasesPeriodontal PocketPeriodontal InflammationSaffronRenalPeriodontitis
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.