Using routine blood and urine sugar tests to predict gestational diabetes after bariatric surgery
Official title: Predictive Value of Glycemic Markers for Gestational Diabetes Mellitus and Pregnancy Complications in Pregnant Women With Prior Bariatric Surgery Who Cannot Tolerate Oral Glucose Tolerance Testing
Run by Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization · NCT07517406 · Data updated 2026-11-12
This project will test whether routine fasting and post-meal blood glucose, HbA1c, and urine glucose can help find gestational diabetes in pregnant women who previously had bariatric surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 50 Years |
| Sex | Women only |
| Enrollment | 84 (estimated) |
| Sponsor | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization Academic / other |
| Locations | 1 site (Istanbul, Şişli) |
| Status | Recruiting |
| Started | February 1, 2026 |
| Main results expected | December 2027 |
| Study ends | December 2027 |
| Registry record updated | April 8, 2026 |
| Trial ID | NCT07517406 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Pregnant women aged 18–50 with a singleton pregnancy, prior bariatric surgery, and ongoing antenatal care at Prof. Dr. Cemil Taşcıoğlu City Hospital with available routine glycemic and ultrasound follow-up are ideal candidates.
✕Probably not a fit
Women with pregestational diabetes, multiple pregnancies, chronic systemic diseases, or incomplete follow-up data are excluded and unlikely to benefit from the study's diagnostic findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective observational cohort conducted at Prof. Dr. Cemil Taşcıoğlu City Hospital enrolling pregnant women aged 18–50 with prior bariatric surgery. Participants will be recruited in the first or second trimester and categorized by whether they tolerate the 75 g OGTT. Routine antenatal glycemic measures (fasting and postprandial glucose, HbA1c, urine glucose) and ultrasound findings will be collected and pregnancy outcomes including GDM, macrosomia, and polyhydramnios recorded. Multivariable logistic regression will be used to test how well these routinely measured markers predict GDM and related complications.
Why it matters
Potential benefit: If successful, this approach could provide a simpler, better-tolerated way to screen for gestational diabetes in women after bariatric surgery, reducing missed diagnoses and OGTT-related side effects.
How similar studies have gone: Prior studies of alternative glycemic markers in pregnancy are limited with mixed results, and applying these markers specifically to post-bariatric patients is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria * Pregnant women aged 18-50 years * Singleton pregnancy * History of bariatric surgery prior to pregnancy * Followed at Prof. Dr. Cemil Taşcıoğlu City Hospital, Department of Obstetrics and Gynecology * Availability of glycemic parameters during early pregnancy (≤14 weeks) and/or between 24 and 28 weeks of gestation (fasting plasma glucose, HbA1c, urine glucose, and/or OGTT results if tolerated) * Availability of sonographic and clinical follow-up data between 28 weeks of gestation and delivery (up to 40 weeks) Exclusion Criteria * Age \<18 years or \>50 years * Multiple pregnancy * Presence of known chronic systemic disease (e.g., pregestational diabetes or endocrine disorders) * Incomplete or missing clinical data
Where it's running
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Prof. Dr. Cemil Taşcıoğlu City Hospital
Istanbul, Şişli, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Burak Deniz AYDOĞDU, MD — Prof. Dr. Cemil Taşcıoğlu City Hospital, Department of Obstetrics and Gynecology
- Study coordinator: Burak Deniz AYDOĞDU, MD
- Email: burakd.1992@hotmail.com
- Phone: 90 539-618-22-28
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.