Using renal resistive index to predict acute kidney injury in high-risk patients
Renal Resistive Index as a Predictor of Acute Renal Impairment in High-risk Patients Admitted to Surgical Intensive Care Unit.
Aswan University · NCT06386796
This study is testing if measuring kidney blood flow using ultrasound can help doctors spot acute kidney injury earlier in high-risk patients in the intensive care unit.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Aswan University (other) |
| Locations | 1 site (Aswān, Aswan Governorate) |
| Trial ID | NCT06386796 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of measuring renal resistive index (RRI) via bedside Doppler ultrasound in identifying acute kidney injury (AKI) among high-risk patients in a surgical intensive care unit. It compares RRI with traditional renal biomarkers and assessments such as urine output and serum creatinine levels. The goal is to enhance early detection of AKI, which is crucial for improving patient outcomes in critically ill individuals. The study is conducted at Aswan University Hospital, focusing on patients with conditions like severe pre-eclampsia, polytrauma, and sepsis.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 years with severe pre-eclampsia, polytrauma, or sepsis admitted to the ICU.
Not a fit: Patients with known chronic kidney disease, congenital renal anomalies, or those who have undergone renal transplantation may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved early detection of acute kidney injury, potentially reducing hospital stays and mortality rates in critically ill patients.
How similar studies have performed: Other studies have explored similar approaches using renal biomarkers for AKI detection, indicating potential for success in this area.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with severe pre-eclampsia and eclampsia. * Polytraumatized patients. * Patients admitted to ICU with sepsis. * Both genders. * Patients above 18 years. Exclusion Criteria: * patients known to have CKD. * patients with congenital renal anomalies. * patients with renal transplantation.
Where this trial is running
Aswān, Aswan Governorate
- Aswan University — Aswān, Aswan Governorate, Egypt (RECRUITING)
Study contacts
- Principal investigator: Mohamed H Abolwafa, MSc — Aswan University
- Study coordinator: Soudy S Hammad, MD
- Email: soudi.salah@aswu.edu.eg
- Phone: 201014761523
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Acute Kidney Injury, Critical Illness, renal resisitive index, surgical ICU, Cystatin C