Using renal resistive index to predict acute kidney injury in high-risk patients
Official title: Renal Resistive Index as a Predictor of Acute Renal Impairment in High-risk Patients Admitted to Surgical Intensive Care Unit.
Run by Aswan University · NCT06386796 · Data updated 2026-11-12
This study is testing if measuring kidney blood flow using ultrasound can help doctors spot acute kidney injury earlier in high-risk patients in the intensive care unit.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Aswan University Academic / other |
| Locations | 1 site (Aswān, Aswan Governorate) |
| Status | Recruiting |
| Started | April 1, 2024 |
| Main results expected | October 1, 2026 |
| Study ends | October 1, 2026 |
| Registry record updated | March 10, 2026 |
| Trial ID | NCT06386796 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults over 18 years with severe pre-eclampsia, polytrauma, or sepsis admitted to the ICU.
✕Probably not a fit
Patients with known chronic kidney disease, congenital renal anomalies, or those who have undergone renal transplantation may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effectiveness of measuring renal resistive index (RRI) via bedside Doppler ultrasound in identifying acute kidney injury (AKI) among high-risk patients in a surgical intensive care unit. It compares RRI with traditional renal biomarkers and assessments such as urine output and serum creatinine levels. The goal is to enhance early detection of AKI, which is crucial for improving patient outcomes in critically ill individuals. The study is conducted at Aswan University Hospital, focusing on patients with conditions like severe pre-eclampsia, polytrauma, and sepsis.
Why it matters
Potential benefit: If successful, this study could lead to improved early detection of acute kidney injury, potentially reducing hospital stays and mortality rates in critically ill patients.
How similar studies have gone: Other studies have explored similar approaches using renal biomarkers for AKI detection, indicating potential for success in this area.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with severe pre-eclampsia and eclampsia. * Polytraumatized patients. * Patients admitted to ICU with sepsis. * Both genders. * Patients above 18 years. Exclusion Criteria: * patients known to have CKD. * patients with congenital renal anomalies. * patients with renal transplantation.
Where it's running
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Aswan University
Aswān, Aswan Governorate, Egypt Recruiting
Study contacts
- Principal investigator: Mohamed H Abolwafa, MSc — Aswan University
- Study coordinator: Soudy S Hammad, MD
- Email: soudi.salah@aswu.edu.eg
- Phone: 201014761523
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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-
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-
Choosing Wisely recommendations for care in the intensive care unit
This project will try the Choosing Wisely approach in adult ICU patients in Sweden to see if using fewer unnecessary tests and interventions is safe.
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Comparing standard and low-dose continuous renal replacement therapy for acute kidney injury
This study tests whether using a standard dose or a lower dose of a kidney treatment can help critically ill patients with acute kidney injury recover better.
-
Understanding brain health in ICU patients with kidney injury
This study looks at how kidney injury affects brain health in critically ill adults in the ICU to see if measuring brain oxygen levels can help predict long-term thinking and memory problems.
-
Using albumin to improve recovery in critically ill patients with acute kidney injury
This study is testing whether giving critically ill patients with acute kidney injury a special type of albumin instead of regular saline can help them recover better and need less kidney treatment.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.