Clinical trial Recruiting at 1 site Observational Ages 18 to 80

Using renal resistive index to predict acute kidney injury in high-risk patients

Official title: Renal Resistive Index as a Predictor of Acute Renal Impairment in High-risk Patients Admitted to Surgical Intensive Care Unit.

Run by Aswan University · NCT06386796 · Data updated 2026-11-12

This study is testing if measuring kidney blood flow using ultrasound can help doctors spot acute kidney injury earlier in high-risk patients in the intensive care unit.

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Quick facts

Study typeObservational
Ages18 Years to 80 Years
SexAll
Enrollment100 (estimated)
SponsorAswan University
Academic / other
Locations1 site (Aswān, Aswan Governorate)
StatusRecruiting
StartedApril 1, 2024
Main results expectedOctober 1, 2026
Study endsOctober 1, 2026
Registry record updatedMarch 10, 2026
Trial IDNCT06386796 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults over 18 years with severe pre-eclampsia, polytrauma, or sepsis admitted to the ICU.

Probably not a fit

Patients with known chronic kidney disease, congenital renal anomalies, or those who have undergone renal transplantation may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of measuring renal resistive index (RRI) via bedside Doppler ultrasound in identifying acute kidney injury (AKI) among high-risk patients in a surgical intensive care unit. It compares RRI with traditional renal biomarkers and assessments such as urine output and serum creatinine levels. The goal is to enhance early detection of AKI, which is crucial for improving patient outcomes in critically ill individuals. The study is conducted at Aswan University Hospital, focusing on patients with conditions like severe pre-eclampsia, polytrauma, and sepsis.

Why it matters

Potential benefit: If successful, this study could lead to improved early detection of acute kidney injury, potentially reducing hospital stays and mortality rates in critically ill patients.

How similar studies have gone: Other studies have explored similar approaches using renal biomarkers for AKI detection, indicating potential for success in this area.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with severe pre-eclampsia and eclampsia.
* Polytraumatized patients.
* Patients admitted to ICU with sepsis.
* Both genders.
* Patients above 18 years.

Exclusion Criteria:

* patients known to have CKD.
* patients with congenital renal anomalies.
* patients with renal transplantation.

Where it's running

  • Aswan University
    Aswān, Aswan Governorate, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.