Using Raman Spectroscopy to assess skin cancer tumors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the effectiveness of Raman Spectroscopy, a non-invasive imaging technique, in determining the size and spread of skin cancer tumors, specifically basal cell carcinoma and squamous cell carcinoma. By utilizing a handheld probe that emits laser light, the study seeks to identify the microscopic infiltration of cancerous tissues beyond what is visibly apparent. The findings could enhance the accuracy of skin brachytherapy treatments while minimizing radiation exposure to critical cosmetic areas. Advanced machine learning algorithms will be employed to analyze the data collected during the study.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Histologically confirmed skin cancer (either basal cell carcinoma or squamous cell carcinoma)
* Participants must plan to receive brachytherapy treatment for the skin cancer at the study site.
* Ability to provide consent to the study.

Exclusion Criteria:

* Patient belongs to a vulnerable population (Minors (under 18 years old), Adults unable to consent, prisoners).
* Lesions on the eyelid or in close proximity to the eye
* Pregnant women, or women of childbearing age who refuse pregnancy testing.
* Patient has pacemaker.

Where it's running

• Stony Brook Hospital
  Stony Brook, New York, United States Recruiting

Study contacts

• Principal investigator: Tiezhi Zhang — Stony Brook Cancer Center
• Study coordinator: Tiezhi Zhang
• Email: tiezhi.zhang@stonybrookmedicine.edu
• Phone: 631-444-3617

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Methionine-Reduced Diet in Solid Tumors (early-phase)

  A small pilot study will test whether a methionine-reduced diet can change blood levels in adults with various solid tumors who are receiving standard cancer therapy.

  Recruiting Early Phase 1 University of California, Irvine · Orange, California · NCT07628634

• In-home cancer treatment with remote specialist support for patients in the Florida Panhandle

  This program will try giving standard cancer treatments at home to people living in the Florida Panhandle and nearby areas to see if they prefer it and have better treatment satisfaction.

  Recruiting Phase 2 Mayo Clinic · Jacksonville, Florida · NCT07285044

• Vitamin D and light therapy to boost skin cancer response before surgery

  This study tests whether giving Vitamin D or a placebo around the time of a light-based treatment (PDT) can help boost skin cancer treatment before Mohs surgery or ED&C in adults with basal cell or squamous cell carcinoma.

  Recruiting Case Comprehensive Cancer Center · Cleveland, Ohio · NCT07241585

• Fractional laser plus tirbanibulin ointment for basal and squamous cell skin cancers

  This trial will try combining fractional laser treatment with tirbanibulin ointment to see if it can treat biopsy-confirmed basal cell and squamous cell skin cancers and reduce the need for surgery.

  Recruiting Phase 1/2 Bruce Robinson, MD · New York, New York · NCT07010692

• Alpha DaRT treatment for skin squamous cell cancer in immunocompromised patients

  This study tests whether placing Alpha DaRT seeds directly into a skin squamous cell carcinoma can shrink tumors and improve outcomes in people with compromised immune systems.

  Recruiting at 6 sites Alpha Tau Medical LTD. · Gilbert, Arizona and 10 other locations · NCT06615635

• Evaluating oral hedgehog inhibitors for treating basal cell carcinoma in the Netherlands

  This study is testing if two oral medications, vismodegib and sonidegib, can help people with advanced basal cell carcinoma or Gorlin syndrome feel better and improve their condition.

  Recruiting at 7 sites Maastricht University Medical Center · Nijmegen, Gelderland and 7 other locations · NCT05463757

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.