Using Quantra bedside clot testing to guide blood transfusions during liver transplant

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares a transfusion algorithm guided by the Quantra bedside viscoelastic sonorheometry device with a conventional transfusion approach in adults undergoing orthotopic liver transplantation. Participants receive intraoperative haemostatic management according to one of the two predefined algorithms, and transfusion volumes and bleeding-related outcomes are recorded. The trial focuses on real-time guidance of blood-product administration during the perioperative period to respond to dynamic coagulation changes common in end-stage liver disease. Primary outcomes include transfusion requirements and measures of intraoperative bleeding, with safety monitored throughout.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 18 years or older
* Patient with ESLD undergoing liver transplantation
* Individuals affiliated with or beneficiaries of a social security scheme
* Free and informed written consent obtained in writing from the patient, or where applicable from the trusted person/family member/close relative

Non-inclusion Criteria:

* Multi-organ transplantation
* Congenital haemostasis disorder (such as haemophilia)
* Patient under juridical protection (persons deprived of liberty or under curatorship or guardianship or safeguard of justice)
* Pregnant or breast-feeding woman
* Patient already enrolled in another interventional study with primary or secondary objective of reducing perioperative bleeding or transfusion

Where it's running

• Toulouse University Hospital
  Toulouse, France Recruiting

Study contacts

• Principal investigator: Guillaume PORTA BONETE, Md — University Hospital, Toulouse
• Study coordinator: Guillaume PORTA BONETE, Md
• Email: porta-bonete.g@chu-toulouse.fr
• Phone: 561323565

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.