Using probiotics to treat ulcerative colitis and irritable bowel syndrome
Official title: Clinical Efficacy and Mechanism of Probiotics in the Adjuvant Treatment of Ulcerative Colitis and Irritable Bowel Syndrome
Run by The First Affiliated Hospital of Xinxiang Medical College · NCT05652621 · Data updated 2026-11-12
This study is testing if adding probiotics to standard treatment can help people with mild to moderate ulcerative colitis and irritable bowel syndrome feel better.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | The First Affiliated Hospital of Xinxiang Medical College Academic / other |
| Locations | 1 site (Xinxiang, Henan) |
| Status | Recruiting |
| Started | July 31, 2022 |
| Main results expected | January 31, 2024 |
| Study ends | December 31, 2026 |
| Registry record updated | December 15, 2022 |
| Trial ID | NCT05652621 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with mild to moderate ulcerative colitis or irritable bowel syndrome who can swallow probiotic pellets.
✕Probably not a fit
Patients with indeterminate colitis or suspected inflammatory bowel disease may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the efficacy of probiotics in patients diagnosed with mild to moderate ulcerative colitis (UC) and irritable bowel syndrome (IBS). Participants will be randomly assigned to receive either conventional treatment combined with probiotics or a placebo. The study aims to assess the impact of probiotics on intestinal flora, inflammatory markers, and overall gut health. By exploring the mechanisms through which probiotics may alleviate symptoms, the trial seeks to provide new therapeutic options for patients suffering from these conditions.
Why it matters
Potential benefit: If successful, this study could offer a novel and effective treatment option for patients with ulcerative colitis and irritable bowel syndrome.
How similar studies have gone: Other studies have shown promising results with probiotics in managing gut health, indicating potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinical diagnosis of ulcerative colitis * Clinical diagnosis of irritable bowel * Can swallow probiotic pellets as required Exclusion Criteria: * indeterminate colitis,suspected IBD
Where it's running
-
The First Affiliated Hospital of Xinxiang Medical College
Xinxiang, Henan, China Recruiting
Study contacts
- Study coordinator: Minhao M Zheng, undergraduate
- Email: mhzhbz@126.com
- Phone: 15651351756
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A specific probiotic given rectally will be tested in adults with mild-to-moderate ulcerative colitis to see if it can help manage symptoms.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.