Clinical trial Recruiting at 1 site Interventional Ages 18 to 80

Using probiotics to treat ulcerative colitis and irritable bowel syndrome

Official title: Clinical Efficacy and Mechanism of Probiotics in the Adjuvant Treatment of Ulcerative Colitis and Irritable Bowel Syndrome

Run by The First Affiliated Hospital of Xinxiang Medical College · NCT05652621 · Data updated 2026-11-12

This study is testing if adding probiotics to standard treatment can help people with mild to moderate ulcerative colitis and irritable bowel syndrome feel better.

Quick facts

Study typeInterventional
Ages18 Years to 80 Years
SexAll
Enrollment200 (estimated)
SponsorThe First Affiliated Hospital of Xinxiang Medical College
Academic / other
Locations1 site (Xinxiang, Henan)
StatusRecruiting
StartedJuly 31, 2022
Main results expectedJanuary 31, 2024
Study endsDecember 31, 2026
Registry record updatedDecember 15, 2022
Trial IDNCT05652621 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals diagnosed with mild to moderate ulcerative colitis or irritable bowel syndrome who can swallow probiotic pellets.

Probably not a fit

Patients with indeterminate colitis or suspected inflammatory bowel disease may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the efficacy of probiotics in patients diagnosed with mild to moderate ulcerative colitis (UC) and irritable bowel syndrome (IBS). Participants will be randomly assigned to receive either conventional treatment combined with probiotics or a placebo. The study aims to assess the impact of probiotics on intestinal flora, inflammatory markers, and overall gut health. By exploring the mechanisms through which probiotics may alleviate symptoms, the trial seeks to provide new therapeutic options for patients suffering from these conditions.

Why it matters

Potential benefit: If successful, this study could offer a novel and effective treatment option for patients with ulcerative colitis and irritable bowel syndrome.

How similar studies have gone: Other studies have shown promising results with probiotics in managing gut health, indicating potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Clinical diagnosis of ulcerative colitis
* Clinical diagnosis of irritable bowel
* Can swallow probiotic pellets as required

Exclusion Criteria:

* indeterminate colitis,suspected IBD

Where it's running

  • The First Affiliated Hospital of Xinxiang Medical College
    Xinxiang, Henan, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.