Using probiotics to treat ulcerative colitis and irritable bowel syndrome
Clinical Efficacy and Mechanism of Probiotics in the Adjuvant Treatment of Ulcerative Colitis and Irritable Bowel Syndrome
This study is testing if adding probiotics to standard treatment can help people with mild to moderate ulcerative colitis and irritable bowel syndrome feel better.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | The First Affiliated Hospital of Xinxiang Medical College Academic / other |
| Locations | 1 site (Xinxiang, Henan) |
| Trial ID | NCT05652621 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the efficacy of probiotics in patients diagnosed with mild to moderate ulcerative colitis (UC) and irritable bowel syndrome (IBS). Participants will be randomly assigned to receive either conventional treatment combined with probiotics or a placebo. The study aims to assess the impact of probiotics on intestinal flora, inflammatory markers, and overall gut health. By exploring the mechanisms through which probiotics may alleviate symptoms, the trial seeks to provide new therapeutic options for patients suffering from these conditions.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with mild to moderate ulcerative colitis or irritable bowel syndrome who can swallow probiotic pellets.
Not a fit: Patients with indeterminate colitis or suspected inflammatory bowel disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could offer a novel and effective treatment option for patients with ulcerative colitis and irritable bowel syndrome.
How similar studies have performed: Other studies have shown promising results with probiotics in managing gut health, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinical diagnosis of ulcerative colitis * Clinical diagnosis of irritable bowel * Can swallow probiotic pellets as required Exclusion Criteria: * indeterminate colitis,suspected IBD
Where this trial is running
Xinxiang, Henan
- The First Affiliated Hospital of Xinxiang Medical College — Xinxiang, Henan, China (Recruiting)
Study contacts
- Study coordinator: Minhao M Zheng, undergraduate
- Email: mhzhbz@126.com
- Phone: 15651351756
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.