Using probiotics to relieve dry eye symptoms
A Clinical Trial of Dry Eye Symptom Mitigation by Oral Intake of Probiotics
NA · Chung Shan Medical University · NCT05906381
This study is testing if taking a daily probiotic capsule can help adults aged 20 to 65 with dry eye symptoms feel better.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 88 (estimated) |
| Ages | 20 Years to 65 Years |
| Sex | All |
| Sponsor | Chung Shan Medical University (other) |
| Locations | 1 site (Taichung) |
| Trial ID | NCT05906381 on ClinicalTrials.gov |
What this trial studies
This investigation evaluates the effectiveness of a daily oral probiotic capsule in alleviating symptoms of dry eye in adults aged 20 to 65. Participants with confirmed dry eye will be randomly assigned to receive either the probiotic or a placebo for 35 days. Various ocular health parameters, including tear volume and quality, will be assessed before and after the treatment period to determine any improvements. The study employs a randomized, double-blind design to ensure unbiased results.
Who should consider this trial
Good fit: Ideal candidates are adults aged 20 to 65 with a confirmed diagnosis of dry eye and specific test results indicating severity.
Not a fit: Patients with significant ocular diseases or chronic conditions such as diabetes or hypertension may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could provide a novel, non-invasive treatment option for individuals suffering from dry eye symptoms.
How similar studies have performed: While the use of probiotics for various health conditions is gaining interest, this specific application for dry eye symptoms is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * aged between 20 and 65 years * with Schirmer's test results less than 10 mm or Ocular Surface Disease Index more than 25 Exclusion Criteria: * evident ocular diseases such as cornea disease, cataract, vitreous degeneration, glaucoma, and retinopathy. * diabetes * hypertension * or other chronic diseases or belong to vulnerable groups(pregnancy woman, prisoner, ethical minorities, economic or educationally disadvantaged subjects, disabled individuals such as those at terminal stage of tumorigenesis, blindness, terminal ill individuals)
Where this trial is running
Taichung
- Jen-Ai Hospital — Taichung, Taiwan (RECRUITING)
Study contacts
- Principal investigator: David Pei-Cheng Lin — Chung Shan Medical University
- Study coordinator: David Pei-Cheng Lin
- Email: pcl@csmu.edu.tw
- Phone: 886-910-371286
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Dry Eye, probiotics, dry eye, eye sore, eye strain