Using Oxytocin to Improve Wound Healing After Cesarean Sections
Role of Local Skin Incision Infiltration by Oxytocin On Wound Healing of Caesarean Section Scar in Primiparous Women A Double Blind Randomized Controlled Study
NA · Egymedicalpedia · NCT05745935
This study is testing if using oxytocin on the skin during cesarean sections can help first-time moms heal better and avoid problems with their wounds.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 20 Years to 35 Years |
| Sex | Female |
| Sponsor | Egymedicalpedia (industry) |
| Locations | 1 site (Cairo) |
| Trial ID | NCT05745935 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effects of local skin incision infiltration with oxytocin on wound healing in primigravidae women undergoing elective cesarean sections. The study aims to address the high rates of wound complications, such as infections and disruptions, which can significantly impact recovery and quality of life. By utilizing oxytocin, a hormone known for its pain-relieving and anti-inflammatory properties, the trial seeks to enhance the healing process and reduce associated morbidities. Participants will be monitored for wound healing outcomes and any complications following the intervention.
Who should consider this trial
Good fit: Ideal candidates are primigravidae women aged 20-35 years who are scheduled for an elective cesarean section.
Not a fit: Patients who may not benefit include multiparous women, those undergoing emergency cesarean sections, or individuals with chronic diseases such as diabetes or hypertension.
Why it matters
Potential benefit: If successful, this approach could lead to improved wound healing and reduced complications for women undergoing cesarean sections.
How similar studies have performed: While the use of oxytocin in wound healing is a novel approach, similar studies have shown promise in other contexts, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Primigravidae women, * Age group from 20- 35 years old. * Gestational age 37-41 weeks, and * Elective caesarean section due to obstetrics indication. * The patient signed an Informed Consent Form authorizing their inclusion Exclusion Criteria: * Multiparous women, * Assisted vaginal delivery, * Normal vaginal delivery, * Emergency caesarean section, * Preterm pre labour rupture of membrane, * Primiparous women with age above 35 years old, * Primiparous women with known connective tissue disease and * Women suffering from chronic diseases such as diabetes, hypertension, cardiovascular diseases, psychiatric diseases, cancer * Smoking Women
Where this trial is running
Cairo
- Al Amerya hospital — Cairo, Egypt (RECRUITING)
Study contacts
- Principal investigator: Assem Anour, Professor — Al-Azhar University, Faculty of medicine for boys
- Study coordinator: Assem Anour, Professor
- Email: dramoussa77@hotmail.com
- Phone: 01118996837
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Wound Heal, Scar, Previous Cesarean Section, wound healing, Oxytocin, caesarean Section scar, wound complications