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Clinical trial Recruiting at 1 site Observational Ages 20 and up

Using optic nerve sheath diameter and duplex imaging to predict outcomes in cardiac arrest patients

Official title: Optic Nerve Sheath Diameter, Carotid Duplex and Transcranial Duplex as a Prognostic Predicting Factor in Post-cardiac Arrest Patients

Run by National Taiwan University Hospital · NCT04510363 · Data updated 2026-11-12

This study is testing if measurements from the optic nerve and blood flow in the neck can help doctors predict how well patients will recover after a cardiac arrest.

Quick facts

Study typeObservational
Ages20 Years and up
SexAll
Enrollment200 (estimated)
SponsorNational Taiwan University Hospital
Academic / other
Locations1 site (Taipei)
StatusRecruiting
StartedDecember 17, 2019
Main results expectedDecember 31, 2027
Study endsDecember 31, 2027
Registry record updatedOctober 8, 2026
Trial IDNCT04510363 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adult patients who have experienced non-traumatic cardiac arrest and achieved return of spontaneous circulation.

Probably not a fit

Patients who have experienced traumatic cardiac arrests or those who do not achieve return of spontaneous circulation after resuscitation may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the relationship between optic nerve sheath diameter (ONSD), carotid duplex, and transcranial duplex measurements in post-cardiac arrest patients. The aim is to analyze these parameters alongside demographic and resuscitation data to predict neurological outcomes. ONSD is a quick and repeatable measure associated with intracranial pressure, while duplex imaging provides noninvasive assessments of cerebrovascular function. The study seeks to establish these factors as prognostic indicators in the management of post-arrest care.

Why it matters

Potential benefit: If successful, this study could enhance the ability to predict neurological outcomes in cardiac arrest patients, leading to more tailored and effective management strategies.

How similar studies have gone: While the specific combination of ONSD and duplex imaging in this context may be novel, similar studies have shown promising results in using these measures for neuroprognosis.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

. Non-traumatic cardiac arrest adult patients achieving return of spontaneous circulation after resuscitation

Exclusion Criteria:

* traumatic cardiac arrests
* non-traumatic arrest patients without return of spontaneous circulation after resuscitation

Where it's running

  • National Taiwan University Hospital
    Taipei, Taiwan     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.