Using optic nerve sheath diameter and duplex imaging to predict outcomes in cardiac arrest patients
Optic Nerve Sheath Diameter, Carotid Duplex and Transcranial Duplex as a Prognostic Predicting Factor in Post-cardiac Arrest Patients
This study is testing if measurements from the optic nerve and blood flow in the neck can help doctors predict how well patients will recover after a cardiac arrest.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 20 Years and up |
| Sex | All |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Trial ID | NCT04510363 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between optic nerve sheath diameter (ONSD), carotid duplex, and transcranial duplex measurements in post-cardiac arrest patients. The aim is to analyze these parameters alongside demographic and resuscitation data to predict neurological outcomes. ONSD is a quick and repeatable measure associated with intracranial pressure, while duplex imaging provides noninvasive assessments of cerebrovascular function. The study seeks to establish these factors as prognostic indicators in the management of post-arrest care.
Who should consider this trial
Good fit: Ideal candidates for this study are adult patients who have experienced non-traumatic cardiac arrest and achieved return of spontaneous circulation.
Not a fit: Patients who have experienced traumatic cardiac arrests or those who do not achieve return of spontaneous circulation after resuscitation may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the ability to predict neurological outcomes in cardiac arrest patients, leading to more tailored and effective management strategies.
How similar studies have performed: While the specific combination of ONSD and duplex imaging in this context may be novel, similar studies have shown promising results in using these measures for neuroprognosis.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: . Non-traumatic cardiac arrest adult patients achieving return of spontaneous circulation after resuscitation Exclusion Criteria: * traumatic cardiac arrests * non-traumatic arrest patients without return of spontaneous circulation after resuscitation
Where this trial is running
Taipei
- National Taiwan University Hospital — Taipei, Taiwan (Recruiting)
Study contacts
- Principal investigator: Wan-Ching Lien, PhD — National Taiwan University Hospital
- Study coordinator: Wan-Ching Lien, PhD
- Email: wanchinglien@ntu.edu.tw
- Phone: +886-223123456
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.