Using non-invasive neuromodulation to help stroke recovery

Non-invasive Neuromodulation NESA Application in the Rehabilitation of Stroke Sequelae. A Pilot Study

Not applicable Interventional University of Las Palmas de Gran Canaria · NCT05853952

This study is testing whether a new non-invasive treatment using microcurrents can help stroke survivors improve their balance, reduce pain, and manage spasticity.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Las Palmas de Gran Canaria Academic / other
Locations1 site (Las Palmas de Gran Canaria, Las Palmas)
Trial IDNCT05853952 on ClinicalTrials.gov

What this trial studies

This pilot study evaluates the effectiveness of NESA microcurrents as a treatment for various complications following a stroke, including spasticity, balance issues, and pain. It involves 30 stroke patients who are between 6 months and 4 years post-stroke and able to stand upright. Participants will be randomly assigned to either a treatment group receiving real stimulation or a placebo group, with both the physiotherapist and patients unaware of their group assignment. The intervention consists of 20 sessions of treatment, each lasting one hour, using the NESA X-Signal device.

Who should consider this trial

Good fit: Ideal candidates are stroke survivors aged between 6 months and 4 years post-stroke who can stand upright and have the cognitive capacity to participate.

Not a fit: Patients with contraindications such as pacemakers, skin conditions, or cognitive impairments may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could significantly improve recovery outcomes and quality of life for stroke patients.

How similar studies have performed: While this approach is relatively novel, similar studies in neuromodulation have shown promising results in improving rehabilitation outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* People who have suffered a stroke with an evolution between 6 months and 6 years.
* Optimal cognitive capacity and mentally competent to participate in the study and complete the required questionnaires.
* People able of standing upright, including those who need technical aids.

Exclusion Criteria:

* Present some of the contraindications for a treatment with NESA XSIGNAL®: pacemakers, internal bleeding, not to apply electrodes on skin in bad condition, with ulcerations or wounds, acute febrile processes, acute thrombophlebitis and/or phobia to electricity.
* Not having signed the informed consent form.
* Presenting any additional injury or pathology during the study.
* Not having the optimal cognitive capacities for understanding and participating in the study.

Where this trial is running

Las Palmas de Gran Canaria, Las Palmas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Strokephysical therapy modalityElectric Stimulation Therapy
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.