Using music to reduce stress and pain in critically ill children on mechanical ventilation
Music Listening Interventions for Children Receiving Mechanical Ventilation: A Mechanistic Trial
This study tests whether listening to live or recorded music can help reduce stress and pain in critically ill children on mechanical ventilation.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 171 (estimated) |
| Ages | 2 Months to 17 Years |
| Sex | All |
| Sponsor | University of Pittsburgh Academic / other |
| Locations | 1 site (Pittsburgh, Pennsylvania) |
| Trial ID | NCT05541029 on ClinicalTrials.gov |
What this trial studies
This trial investigates the effects of live and recorded music listening on stress and pain biomarkers in children receiving mechanical ventilation in a pediatric intensive care unit. It employs a randomized within-subject crossover design, allowing each participant to experience both music interventions and standard care. The study aims to identify the mechanisms through which music may alleviate stress and pain, potentially offering a non-pharmacological alternative to traditional analgesic and sedative medications.
Who should consider this trial
Good fit: Ideal candidates are children aged 2 months to 17 years who are intubated and expected to stay in the PICU for more than 72 hours.
Not a fit: Patients who are not expected to survive their PICU stay or have specific medical conditions such as deafness or COVID-19 may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could provide a safer, non-drug method to reduce stress and pain in critically ill children.
How similar studies have performed: Other studies have shown promising results using music interventions for stress and pain management, suggesting this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 2 months -17 years old * intubated and receiving MV * expected to have a PICU stay of \>72 hours Exclusion Criteria: * Primary caregiver does not read, write, and speak English * The child is not expected to survive the PICU stay * The child has deafness in both ears, has a history of musicogenic epilepsy, is receiving neuromuscular blockade infusion * The child has a diagnosis of COVID-19 * The child was admitted for a new traumatic brain injury
Where this trial is running
Pittsburgh, Pennsylvania
- UPMC Children's Hospital of Pittsburgh — Pittsburgh, Pennsylvania, United States (Recruiting)
Study contacts
- Principal investigator: Jessica M Jarvis, PhD — University of Pittsburgh
- Study coordinator: Jessica Eldridge
- Email: eldridgejl@upmc.edu
- Phone: 4126927143
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.