Using MRI to detect bleeding in plaques for stroke diagnosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the relationship between intraplaque hemorrhage (IPH) detected by non-contrast MRI of the carotid artery and acute ischemic stroke events. By analyzing both prospective and retrospective data, the study seeks to determine if identifying IPH can enhance the diagnostic process for stroke patients, particularly those with cryptogenic strokes. The research focuses on integrating simpler imaging protocols into routine clinical practice to better stratify stroke etiology and identify patients at risk for recurrent strokes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with acute ischemic stroke
* Availability of non-contrast carotid MRI scans obtained through routine diagnostic work-up

Exclusion Criteria:

* Infarct in the posterior circulation or bilateral ischemic infarcts
* Time between symptom onset and non-contrast carotid MRI \> 10 days
* Prior stenting of a carotid artery or carotid endarterectomy
* Age \< 18 years
* Life expectancy \< 1 year
* Inability to provide written informed consent

This eligibility criteria apply for the prospective part of the PARADE study.

Where it's running

• Institute for Stroke and Dementia Research
  Munich, Germany Recruiting

Study contacts

• Principal investigator: Anna Kopczak, MD — Institute for Stroke and Dementia Research
• Study coordinator: Martin Dichgans, Prof.
• Email: isd@med.uni-muenchen.de
• Phone: +49 89 4400 46019

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.