Using Moses 2.0 technology for prostate laser treatment

Moses Vaporization: Is Use of Moses 2.0 in Holmium Laser Ablation of the Prostate More Efficient

NA · University of Kansas Medical Center · NCT04979143

This study is testing if a new technology called Moses 2.0 can make laser treatment for an enlarged prostate work better for patients.

Quick facts

PhaseNA
Study typeInterventional
Enrollment124 (estimated)
Ages18 Years and up
SexMale
SponsorUniversity of Kansas Medical Center (other)
Locations1 site (Kansas City, Kansas)
Trial IDNCT04979143 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the efficiency of the Moses 2.0 technology during holmium laser vaporization of the prostate for patients with benign prostatic hyperplasia. Patients will undergo standard preoperative assessments and will be randomized to receive either the standard laser treatment or the treatment enhanced with Moses 2.0 technology. The study will measure various intraoperative parameters, including procedure time and vaporization efficiency, while ensuring that both the surgeon and patient are blinded to the treatment received. Virtual appointments may be offered for certain aspects of the trial to accommodate the ongoing COVID-19 pandemic.

Who should consider this trial

Good fit: Ideal candidates are men over 18 years old with bothersome lower urinary tract symptoms who choose surgical management and have a prostate size of 60 grams or less.

Not a fit: Patients with a current diagnosis of prostate cancer, urinary retention, or those on anticoagulation therapy may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more efficient and effective treatment options for patients suffering from lower urinary tract symptoms due to benign prostatic hyperplasia.

How similar studies have performed: While this approach is innovative, similar studies have shown promise in improving surgical outcomes with advanced laser technologies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients \> 18 years of age
* Patients with bothersome lower urinary tract symptoms who opt for surgical management
* Prostate size 60g or less

Exclusion Criteria:

* Current use of anticoagulation or antiplatelet agent Aspirin 81 use is okay and can be continued through the study
* Bleeding diathesis
* AUA symptom score \< 9
* Current urinary retention
* Known diagnosis of prostate cancer
* Known diagnosis of neurogenic bladder

Where this trial is running

Kansas City, Kansas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.