Using molecular hydrogen to improve weight loss in overweight and obese adolescents
Evaluation of Molecular Hydrogen Supplementation to Enhance the Efficacy of Weight Loss Retreat in Overweight and Obese Adolescents. A Randomized, Double-blind, Parallel-group, Placebo-controlled Trial
This study is testing if drinking hydrogen-rich water can help overweight and obese teenagers lose more weight during a 4-week weight loss program.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 11 Years to 18 Years |
| Sex | All |
| Sponsor | Palacky University Academic / other |
| Locations | 1 site (Olomouc, Czech Republic) |
| Trial ID | NCT06961110 on ClinicalTrials.gov |
What this trial studies
This randomized controlled trial investigates the impact of molecular hydrogen supplementation on the effectiveness of a 4-week weight loss retreat for overweight and obese adolescents. Participants will be randomly assigned to receive either hydrogen-rich water or a placebo while following a structured diet and exercise program. The study will assess various health outcomes, including body composition, insulin sensitivity, lipid profiles, and markers of oxidative stress. A total of 60 participants will be monitored throughout the retreat and during follow-up assessments.
Who should consider this trial
Good fit: Ideal candidates are overweight or obese adolescents aged 5-19 years with a regular menstrual cycle.
Not a fit: Patients with high blood pressure, dyslipoproteinemia, cardio-respiratory disorders, or musculoskeletal disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance weight loss outcomes and improve metabolic health in adolescents.
How similar studies have performed: While the use of molecular hydrogen is a novel approach, similar studies exploring its effects on metabolic health have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Body mass index indicating overweight or obesity, as determined according to the World Health Organization's international percentile charts for children aged 5-19 years. * Presence of a regular menstrual cycle in female participants. * Signed informed consent from the legal representative. Exclusion Criteria: * High blood pressure. * Dyslipoproteinemia. * Cardio-respiratory disorders. * Musculoskeletal disorders. * Use of any medications regulating heart rhythm or the neurovegetative and hormonal system.
Where this trial is running
Olomouc, Czech Republic
- Palacky University, Faculty of Physical Culture — Olomouc, Czech Republic, Czechia (Recruiting)
Study contacts
- Principal investigator: Darja Supikova — Palacky University, Faculty of Physical Culture
- Study coordinator: Darja Supikova
- Email: darja.supikova@upol.cz
- Phone: +420585636731
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.