Using mobile therapy to help people with alcohol use disorder
Integration of Neurofunctional Phenotyping Into a Preliminary Investigation of Stand-alone Web-based Cognitive Behavioral Therapy (CBT4CBT) for Alcohol Use Disorder
NA · Virginia Commonwealth University · NCT06190236
This study is testing whether a new mobile therapy can help people with alcohol use disorder who aren't currently in treatment by personalizing the approach based on their brain function.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 278 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Virginia Commonwealth University (other) |
| Locations | 1 site (Richmond, Virginia) |
| Trial ID | NCT06190236 on ClinicalTrials.gov |
What this trial studies
This project aims to explore the feasibility of integrating neurofunctional phenotyping with mobile cognitive behavioral therapy (CBT4CBT) for individuals with alcohol use disorder (AUD) who are not currently seeking treatment. By utilizing a neuroscience-based framework, the study seeks to tailor treatment approaches based on individual neurofunctional profiles, potentially improving outcomes for those with AUD. The intervention will be delivered through a web-based platform, making it accessible to participants who have access to a smart mobile device or computer. The study focuses on understanding how personalized treatment can enhance the effectiveness of behavioral therapies for AUD.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who meet the DSM-5 criteria for alcohol use disorder and report recent heavy alcohol use.
Not a fit: Patients currently receiving specialized professional substance use disorder treatment may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more effective and personalized treatment options for individuals struggling with alcohol use disorder.
How similar studies have performed: While the integration of neurofunctional phenotyping in behavioral treatments for AUD is a novel approach, previous studies have shown promise in using precision medicine strategies for substance use disorders.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * at least 18 years of age * Male or female sex assigned at birth * Meet DSM-5 Alcohol Use Disorder criteria * report recent heavy alcohol use during the past month * access to a smart mobile device or computer * English-speaking. * We are not excluding any participants based on gender identity. Exclusion Criteria: * currently receiving specialized professional SUD treatment * presenting with language barriers, cognitive impairment, or serious medical or psychiatric illness that would preclude them from providing informed consent or participating in the ResearchMatch.
Where this trial is running
Richmond, Virginia
- Virginia Commonwealth University — Richmond, Virginia, United States (RECRUITING)
Study contacts
- Principal investigator: Dace Svikis — Virginia Commonwealth University
- Study coordinator: Dace Svikis
- Email: dssvikis@vcu.edu
- Phone: (804) 827-1184
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Alcohol Abuse, Alcohol Use Disorder